University of Missouri-Kansas City, Kansas City, MO, USA.
Rheumatol Int. 2012 Jan;32(1):1-3. doi: 10.1007/s00296-011-2000-1. Epub 2011 Jul 23.
The treatment of severe and refractory cases of reactive arthritis is not well defined. There is a limited data about the use of tumor necrosis factor-α (TNF-α) blockers in reactive arthritis. Herein is a description of a patient with severe case of Chlamydia trachomatis-related reactive arthritis that was refractory to nonsteroidal anti-inflammatory drugs, sulfasalazine, prednisone, and methotrexate and was successfully treated with etanercept.
对于严重和难治性反应性关节炎病例,其治疗方法尚未明确。关于肿瘤坏死因子-α(TNF-α)阻滞剂在反应性关节炎中的应用,目前数据有限。本文描述了一例严重的衣原体相关反应性关节炎患者,该患者对非甾体抗炎药、柳氮磺胺吡啶、泼尼松和甲氨蝶呤均无反应,后使用依那西普成功治疗。