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[萎缩性硬化性苔藓样皮炎。皮肤梗死的发病机制、诊断与治疗]

[Livedoid vasculopathy. Pathogenesis, diagnosis and treatment of cutaneous infarction].

作者信息

Goerge T

机构信息

Hautklinik, Universitätsklinikum Münster.

出版信息

Hautarzt. 2011 Aug;62(8):627-34; quiz 635. doi: 10.1007/s00105-011-2172-3.

Abstract

Livedo vasculopathy is a chronic recurrent disease of the cutaneous circulation and is characterized by episodic occurrence of painful ulcerations of the lower leg. These heal slowly leaving small porcelain-white scars called atrophie blanche. Recent research has shown that livedoid vasculopathy is a coagulation disorder classified as a vasculopathy different from inflammatory vasculitis. Distinguishing between the disorders enhances the pathophysiologic understanding and supports the therapeutic rationale. The prevention of irreversible residual scarring is the main goal in treating cutaneous infarction; prompt treatment is required.

摘要

青斑样血管病是一种皮肤循环的慢性复发性疾病,其特征是小腿反复出现疼痛性溃疡。这些溃疡愈合缓慢,会留下称为白色萎缩的小瓷白色疤痕。最近的研究表明,类脂质渐进性坏死性皮病是一种凝血障碍,被归类为不同于炎症性血管炎的血管病。区分这些疾病有助于增强对病理生理学的理解,并支持治疗原理。预防不可逆的残留疤痕是治疗皮肤梗死的主要目标;需要及时治疗。

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