Health Services Research Unit, IDI IRCCS, Via Monti di Creta 104, 00157 Rome, Italy.
Br J Dermatol. 2011 Dec;165(6):1190-6. doi: 10.1111/j.1365-2133.2011.10532.x.
In dermatological research and clinical practice it is important to evaluate the burden of the disease.
To assess whether the 12-item Short Form of the Medical Outcomes Study (SF-12) could yield a valid description of the health status of a large number of dermatological outpatients.
The SF-12 and the 12-item General Health Questionnaire (GHQ-12) were utilized. Questionnaires were self-completed by the outpatients in the waiting rooms. At the end of the visit the dermatologists recorded the diagnosis and the evaluation of the clinical severity.
Data were complete for 2499 patients. We observed a reduction in the Physical Component Summary score (PCS-12) with increasing age, while the Mental Component Summary score (MCS-12) was stable. PCS-12 and MCS-12 scores were worse in women. Twenty-three per cent of patients were identified as GHQ-12 positive. GHQ-12-positive patients ('cases') had lower PCS-12 and MCS-12 scores compared with GHQ-12-negative patients (mean ± SD, PCS-12: 47·9 ± 10·8 vs. 52·2 ± 6·6; MCS-12: 35·2 ± 10·2 vs. 50·9 ± 78·3, respectively). High correlations between the MCS-12 score and the GHQ-12 were documented overall (-0·690, P < 0·001) and for single skin diseases.
The impact of dermatological diseases is high for the mental components of health status; the mean scores for MCS-12 were low, and lower in patients identified as GHQ-12 'cases'. The picture of the general health status of patients with skin diseases given by the SF-12 allows meaningful comparisons both within dermatological conditions and with diseases in other specialties, as well as within categories of clinical severity and psychological well-being in single skin conditions.
在皮肤科研究和临床实践中，评估疾病负担很重要。
评估 12 项简明健康状况量表（SF-12）是否能够对大量皮肤科门诊患者的健康状况进行有效描述。
使用 SF-12 和 12 项一般健康问卷（GHQ-12）。患者在候诊室自行填写问卷。就诊结束时，皮肤科医生记录诊断和临床严重程度评估。
共 2499 例患者的数据完整。我们观察到生理成分综合评分（PCS-12）随年龄增长而降低，而心理成分综合评分（MCS-12）则保持稳定。女性的 PCS-12 和 MCS-12 评分较低。23%的患者被确定为 GHQ-12 阳性。与 GHQ-12 阴性患者相比，GHQ-12 阳性患者（“病例”）的 PCS-12 和 MCS-12 评分较低（平均 ± 标准差，PCS-12：47.9 ± 10.8 对 52.2 ± 6.6；MCS-12：35.2 ± 10.2 对 50.9 ± 78.3）。总体上，MCS-12 评分与 GHQ-12 之间存在高度相关性（-0.690，P < 0.001），且与单一皮肤病也存在相关性。
皮肤病对健康状况的心理成分影响较大；MCS-12 的平均得分较低，且在被确定为 GHQ-12“病例”的患者中得分更低。SF-12 给出的皮肤病患者一般健康状况图像可以在皮肤科疾病和其他专科疾病之间、在单一皮肤病的临床严重程度和心理幸福感类别内进行有意义的比较。
