Division of Pediatric General and Thoracic Surgery, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, Faculty Pavilion 7th Floor, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.
Surg Clin North Am. 2011 Aug;91(4):771-85, viii. doi: 10.1016/j.suc.2011.05.001.
Important advances in the study of bacteria associated with the human gastrointestinal tract have significant implications for clinicians striving to meet the metabolic and nutritional needs of critically ill patients. This article offers a broad overview of the importance of the host-microbe relationship, discusses what is currently known about the role of gut microbes in nutrition and metabolism in the healthy human host, reviews how gut microbes are affected by critical illness, and discusses interventions that have already been used to manipulate the gut microbiome in patients in the intensive care unit.
在研究与人类胃肠道相关的细菌方面取得的重要进展，对临床医生努力满足重症患者的代谢和营养需求具有重要意义。本文全面概述了宿主-微生物关系的重要性，讨论了目前已知的肠道微生物在健康人体宿主中的营养和代谢中的作用，回顾了肠道微生物如何受危重病影响，并讨论了已经用于在重症监护病房中操纵肠道微生物组的干预措施。
