Chairman, Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, 1025 Walnut Street, Suite 1112, Philadelphia, PA 19107, USA.
Ther Adv Urol. 2010 Aug;2(4):171-81. doi: 10.1177/1756287210375270.
Hormonal therapy has been the standard for advanced prostate cancer for over 60 years. Recently, the utility of androgen ablation through various means has been demonstrated for earlier stages of disease. In particular, the strongest evidence to date involves the use of hormonal therapy in combination with radiation therapy. In this article we review the basic concepts in hormonal ablation for prostate cancer and review the evidence-based studies that support the use of hormonal therapy in early stage prostate cancer.
激素治疗已经成为 60 多年来治疗晚期前列腺癌的标准方法。最近,通过各种手段进行雄激素阻断的方法在疾病早期阶段的应用也得到了证实。特别是,迄今为止最有力的证据涉及到联合使用激素治疗和放射治疗。在本文中,我们回顾了前列腺癌激素消融的基本概念,并回顾了支持在早期前列腺癌中使用激素治疗的基于证据的研究。