Drucker C R
Baylor College of Medicine, Houston, Tex.
Dermatologica. 1990;180(2):90-2. doi: 10.1159/000247999.
A patient with malignant atrophic papulosis (Degos' disease) is studied. Platelet function studies showed abnormalities of increased adhesiveness and aggregation. Treatment with dipyridamole and aspirin correlated with reversal of these abnormalities and cessation of new lesion development. When treatment was stopped, platelet function abnormalities and new skin lesions developed within 2 months. With reinstitution of therapy, the patient developed no new lesions in the 5 months he was followed. This is the second report of platelet function abnormality and apparent successful treatment with antiplatelet therapy in a patient with Degos' disease.
对一名患有恶性萎缩性丘疹病（德戈斯病）的患者进行了研究。血小板功能研究显示黏附性和聚集性增加的异常情况。使用双嘧达莫和阿司匹林治疗与这些异常情况的逆转以及新病变发展的停止相关。当治疗停止时，血小板功能异常和新的皮肤病变在2个月内出现。随着治疗的重新开始，在对该患者进行随访的5个月里未出现新的病变。这是第二例关于德戈斯病患者血小板功能异常以及抗血小板治疗明显成功的报告。
