Department of Urology, Fredericia Hospital, University of Southern Denmark, Fredericia, Denmark.
J Endourol. 2011 Oct;25(10):1627-32. doi: 10.1089/end.2011.0146. Epub 2011 Jul 26.
This study compared the characteristics and outcomes of percutaneous nephrolithotomy (PCNL) in patients with and without renal malformations using the Clinical Research Office of the Endourological Society (CROES) PCNL Global Study database.
The CROES PCNL Global Study collected prospective data for consecutive patients who were treated with PCNL at centers around the world during 1 year. Patient characteristics, operative data, and outcomes of PCNL in patients with renal anomalies and those with normal kidneys were compared.
Of 5542 patients whose renal anatomy was recorded, 202 (3.6%) patients had a renal malformation. The most frequent anomalies were horseshoe kidneys (1.8%) and malrotated kidneys (1.3%). The prone position was the most frequently used position for patients with renal anomalies as was upper pole puncture. PCNL achieved stone-free rates of 76.6% in patients with anomalous kidneys and 76.2% in those with normal kidneys. The frequency of complications was similar in the two groups. Median operative time was significantly longer (87 min vs 75 min, P=0.037), and access for PCNL was unsuccessful in significantly more patients (5% vs 1.7%, P=0.001) in whom renal anomalies were present.
In patients undergoing PCNL, the presence of renal malformation is likely to extend operative time. Stone-free rates as well as incidence of complications after PCNL are similar irrespective of the presence of renal anomalies.
本研究通过临床研究办公室泌尿外科学会(CROES)经皮肾镜取石术(PCNL)全球研究数据库,比较了有和无肾畸形患者行 PCNL 的特征和结局。
CROES PCNL 全球研究在全球范围内的中心收集了接受 PCNL 治疗的连续患者的前瞻性数据,为期 1 年。比较了肾畸形患者和正常肾脏患者的患者特征、手术数据和 PCNL 结局。
在记录了肾脏解剖结构的 5542 名患者中,有 202 名(3.6%)患者存在肾畸形。最常见的异常是马蹄肾(1.8%)和肾旋转不良(1.3%)。肾畸形患者中最常采用的体位是俯卧位,而上极穿刺最常用。PCNL 在异常肾患者中的结石清除率为 76.6%,在正常肾患者中为 76.2%。两组并发症的发生率相似。中位手术时间明显延长(87 分钟比 75 分钟,P=0.037),而且肾畸形患者中 PCNL 通路不成功的频率明显更高(5%比 1.7%,P=0.001)。
在接受 PCNL 的患者中,肾畸形的存在可能会延长手术时间。无论是否存在肾畸形,PCNL 后的结石清除率和并发症发生率相似。