Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200f - bus 02404, 3001 Heverlee (Leuven), Belgium.
Chem Soc Rev. 2012 Feb 7;41(3):1130-72. doi: 10.1039/c1cs15132k. Epub 2011 Jul 28.
This critical review covers the advances made using the 4-bora-3a,4a-diaza-s-indacene (BODIPY) scaffold as a fluorophore in the design, synthesis and application of fluorescent indicators for pH, metal ions, anions, biomolecules, reactive oxygen species, reactive nitrogen species, redox potential, chemical reactions and various physical phenomena. The sections of the review describing the criteria for rational design of fluorescent indicators and the mathematical expressions for analyzing spectrophotometric and fluorometric titrations are applicable to all fluorescent probes (206 references).
这篇评论综述了 4-硼-3a,4a-二氮杂-s-茚满（BODIPY）作为荧光团在设计、合成和应用用于 pH 值、金属离子、阴离子、生物分子、活性氧物种、活性氮物种、氧化还原电位、化学反应和各种物理现象的荧光指示剂方面的进展。综述中描述荧光指示剂合理设计的标准以及分析分光光度和荧光滴定的数学表达式的部分适用于所有荧光探针（206 篇参考文献）。
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