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与印度大学生在大流行后期对 2009 年甲型 H1N1 流感疫苗接种接受相关的因素。

Factors associated with 2009 pandemic influenza A (H1N1) vaccination acceptance among university students from India during the post-pandemic phase.

机构信息

Centre for Biomedical Research, Vellore Institute of Technology University, Vellore, India.

出版信息

BMC Infect Dis. 2011 Jul 29;11:205. doi: 10.1186/1471-2334-11-205.

Abstract

BACKGROUND

There was a low adherence to influenza A (H1N1) vaccination program among university students and health care workers during the pandemic influenza in many parts of the world. Vaccination of high risk individuals is one of the recommendations of World Health Organization during the post-pandemic period. It is not documented about the student's knowledge, attitude and willingness to accept H1N1 vaccination during the post-pandemic period. We aimed to analyze the student's knowledge, attitude and willingness to accept H1N1 vaccination during the post-pandemic period in India.

METHODS

Vaccine against H1N1 was made available to the students of Vellore Institute of Technology, India from September 2010. The data are based on a cross-sectional study conducted during October 2010 to January 2011 using a self-administered questionnaire with a representative sample of the student population (N = 802).

RESULTS

Of the 802 respondents, only 102/802 (12.7%) had been vaccinated and 105/802 (13%) planned to do so in the future, while 595/802 (74%) would probably or definitely not get vaccinated in the future. The highest coverage was among the female (65/102, 63.7%) and non-compliance was higher among men in the group (384/595; 64.5%) (p < 0.0001). The representation of students from school of Bio-sciences and Bio-technology among vaccinees is significantly higher than that of other schools. Majority of the study population from the three groups perceived vaccine against H1N1 as the effective preventive measure when compared to other preventive measures. 250/595 (42%) of the responders argued of not being in the risk group. The risk perception was significantly higher among female (p < 0.0001). With in the study group, 453/802 (56.4%) said that they got the information, mostly from media.

CONCLUSIONS

Our study shows that the vaccination coverage among university students remains very low in the post-pandemic period and doubts about the safety and effectiveness of the vaccine are key elements in their rejection. Our results indicate a need to provide accessible information about the vaccine safety by scientific authorities and fill gaps and confusions in this regard.

摘要

背景

在世界许多地区的大流行流感期间,大学生和医护人员对接种甲型 H1N1 流感疫苗的依从性较低。在大流行后期,世界卫生组织建议对高危人群进行疫苗接种。关于大流行后期学生对 H1N1 疫苗的知识、态度和接受意愿,目前尚未有相关记录。我们旨在分析印度大流行后期学生对 H1N1 疫苗的知识、态度和接受意愿。

方法

2010 年 9 月,印度维洛尔科技大学向学生提供 H1N1 疫苗。本数据基于 2010 年 10 月至 2011 年 1 月期间进行的一项横断面研究,使用自我管理问卷对学生人群(N=802)进行了代表性抽样。

结果

在 802 名受访者中,仅有 102/802(12.7%)人已接种疫苗,105/802(13%)人计划未来接种疫苗,而 595/802(74%)人可能或肯定不会在未来接种疫苗。女性接种率最高(65/102,63.7%),而男性未接种率更高(384/595;64.5%)(p<0.0001)。来自生物科学与生物技术学院的学生在疫苗接种者中的比例明显高于其他学院。与其他预防措施相比,大多数研究人群来自三个组的人都认为甲型 H1N1 疫苗是有效的预防措施。595 名应答者中有 250/595(42%)认为自己不属于风险人群。女性对风险的认识明显更高(p<0.0001)。在研究组内,453/802(56.4%)人表示他们获得了信息,主要来自媒体。

结论

我们的研究表明,大流行后期大学生的疫苗接种覆盖率仍然很低,对疫苗安全性和有效性的怀疑是他们拒绝接种的关键因素。我们的结果表明,需要由科学权威部门提供有关疫苗安全性的可及信息,以填补这方面的空白和消除困惑。

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