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前列腺癌与维生素 D:证据究竟作何提示?

Prostate cancer and vitamin D: what does the evidence really suggest?

机构信息

Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Mail Code L586, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.

出版信息

Urol Clin North Am. 2011 Aug;38(3):333-42. doi: 10.1016/j.ucl.2011.04.007. Epub 2011 Jun 14.

DOI:10.1016/j.ucl.2011.04.007
PMID:21798396
Abstract

The optimal approach to vitamin D supplementation for the average healthy person is debatable. In patients with cancer, the role of vitamin D supplementation, possibly in treatment, is even less clear. Vitamin D is shown to play a role in prostate cancer biology; however, the clinical data have not consistently demonstrated a link. Additional studies are needed to determine if higher doses of vitamin D supplements could benefit selected populations (ie, the elderly or patients with cancer) even if they may not be beneficial for the general population.

摘要

对于一般健康人来说,维生素 D 补充的最佳方法仍存在争议。对于癌症患者,维生素 D 补充(可能在治疗中)的作用则更加不明确。研究表明维生素 D 在前列腺癌生物学中发挥作用;然而,临床数据并未一致显示两者之间存在关联。需要进一步的研究来确定更高剂量的维生素 D 补充剂是否对某些人群(如老年人或癌症患者)有益,即使它们可能对一般人群无益。

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Prostate cancer management: long-term beliefs, epidemic developments in the early twenty-first century and 3PM dimensional solutions.前列腺癌管理:长期观念、21世纪初的流行趋势及三维解决方案
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