Department of Computer Aided Mechanical Design Engineering, Daejin University, Sundan-dong, San 11-1, Pocheon-si 487-711, South Korea.
Biomaterials. 2011 Nov;32(31):7741-54. doi: 10.1016/j.biomaterials.2011.07.019. Epub 2011 Jul 27.
An effective method for the 3D porous scaffold design of human tissue is presented based on a hybrid method of distance field and triply periodic minimal surface (TPMS). By the creative application of traditional distance field algorithm into the Boolean operations of the anatomical model and TPMS-based unit cell library, an almost defects free porous scaffolds having the complicated micro-structure and high quality external surface faithful to a specific anatomic model can be easily obtained without the difficult and time-consuming trimming and re-meshing processes. After generating the distance fields for the given tissue model and required internal micro-structure, a series of simple modifications in distance fields enable us to obtain a complex porous scaffold. Experimental results show that the proposed scaffold design method has the potential to combine the perfectly interconnected pore networks based on the TPMS unit cell libraries and the given external geometry in a consistent framework irrespective of the complexity of the models.
提出了一种基于距离场和三重周期极小曲面（TPMS）混合方法的人体组织 3D 多孔支架设计的有效方法。通过将传统的距离场算法创造性地应用于解剖模型的布尔运算和基于 TPMS 的单元胞库，无需繁琐且耗时的修剪和重新网格化过程，就可以轻松获得具有复杂微观结构和高质量外表面且几乎无缺陷的多孔支架，这些支架忠实于特定的解剖模型。在为给定的组织模型和所需的内部微观结构生成距离场后，通过对距离场进行一系列简单的修改，我们就可以获得复杂的多孔支架。实验结果表明，所提出的支架设计方法具有潜力，可以在不考虑模型复杂性的情况下，将基于 TPMS 单元胞库的完美连通孔网络与给定的外部几何形状结合在一个一致的框架内。
