Bascom Palmer Eye Institute, Miami, FL 33136, USA.
J Neuroophthalmol. 2012 Sep;32(3):197-201. doi: 10.1097/WNO.0b013e3182268746.
Allergic fungal sinusitis (AFS) is thought to represent an immunologic response to exposure to dematiaceous fungi. These fungi are known to cause disease more frequently in hot and humid climates and seasons.
Three patients presented with unusual manifestations of fungal disease after exposure to environments recently affected by hurricanes.
Two patients had AFS, 1 with gradual painless visual loss from an AFS mass extending into the suprasellar region and 1 with orbital apex syndrome. Another patient had invasive fungal disease and developed orbital apex syndrome.
These cases underscore the importance of clinical recognition of fungal disease in patients with sinus, orbital, or skull base involvement as well as its potential for causing permanent visual loss. This report suggests a potential association between fungal disease and tropical storm exposure.
变应性真菌性鼻窦炎（AFS）被认为是对暗色真菌暴露的免疫反应。已知这些真菌在炎热潮湿的气候和季节中更常引起疾病。
有三位患者在接触最近受飓风影响的环境后，表现出真菌病的异常表现。
两名患者患有 AFS，1 名患者因 AFS 肿块延伸至鞍上区而逐渐出现无痛性视力丧失，1 名患者患有眶尖综合征。另一名患者患有侵袭性真菌病并发展为眶尖综合征。
这些病例强调了在鼻窦、眼眶或颅底受累的患者中临床识别真菌病的重要性，以及其导致永久性视力丧失的潜在可能性。本报告提示真菌病与热带风暴暴露之间存在潜在关联。
