Department of Chemistry, University of California, Berkeley, California, USA.
Nat Methods. 2011 Jul 28;8(8):638-42. doi: 10.1038/nmeth.1657.
Bioorthogonal chemistry allows a wide variety of biomolecules to be specifically labeled and probed in living cells and whole organisms. Here we discuss the history of bioorthogonal reactions and some of the most interesting and important advances in the field.
生物正交化学允许对各种生物分子进行特异性标记和探测,用于活细胞和整个生物体。在这里,我们讨论生物正交反应的历史以及该领域一些最有趣和最重要的进展。