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经皮内镜胃造口术的适应证与老年患者的生存率。

Indications for percutaneous endoscopic gastrostomy and survival in old adults.

机构信息

Department of Surgical and Medical Gastroenterology and Hepatology, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Food Nutr Res. 2011;55. doi: 10.3402/fnr.v55i0.6037. Epub 2011 Jul 20.

Abstract

BACKGROUND

Many diseases striking old adults result in eating difficulties. Indications for selecting individuals for percutaneous endoscopic gastrostomy (PEG) are unclear and everybody may not benefit from the procedure.

OBJECTIVE

The aim of this study was to evaluate indications for and survival after PEG insertion in patients older than 65 years.

DESIGN AND METHODS

A retrospective analysis including age, gender, diagnosis, indication, and date of death was made in 201 consecutive individuals, 94 male, mean age 79±7 years, who received a nutritional gastrostomy.

RESULTS

Dysphagia was present in 86% of the patients and stroke was the most common diagnosis (49%). Overall median survival was 123 days and 30-day mortality was 22%. Patients with dementia and Mb Parkinson had the longest survival (i.e. 244 and 233 days), while those with other neurological diseases, and head and neck malignancy had the shortest (i.e. 75 and 106 days). There was no difference in mortality in patients older or younger than 80 years, except in patients with dementia.

CONCLUSIONS

Old age should not be a contraindication for PEG. A high 30-day mortality indicates that there is a need of better criteria for selection and timing of PEG insertion in the elderly.

摘要

背景

许多影响老年人的疾病都会导致进食困难。经皮内镜下胃造口术(PEG)的适应证并不明确,并非所有人都能从该手术中获益。

目的

本研究旨在评估 65 岁以上患者行 PEG 插入术的适应证和生存情况。

设计和方法

回顾性分析了 201 例连续接受营养性胃造口术的患者(94 例男性,平均年龄 79±7 岁)的年龄、性别、诊断、适应证和死亡日期。

结果

86%的患者存在吞咽困难,最常见的诊断是中风(49%)。总体中位生存期为 123 天,30 天死亡率为 22%。痴呆和帕金森病患者的生存期最长(分别为 244 天和 233 天),而其他神经疾病和头颈部恶性肿瘤患者的生存期最短(分别为 75 天和 106 天)。80 岁以上和 80 岁以下患者的死亡率无差异,除痴呆患者外。

结论

高龄不应成为 PEG 的禁忌证。高 30 天死亡率表明,需要更好的标准来选择和确定老年患者行 PEG 插入术的时机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28d1/3144742/c0c528448e23/FNR-55-6037-g001.jpg

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