可重置动态微阵列器件。

A resettable dynamic microarray device.

机构信息

Center for International Research on Micronano Mechatronics-CIRMM, Institute of Industrial Science-IIS, The University of Tokyo, Bunkyo, Japan.

出版信息

Biomed Microdevices. 2011 Dec;13(6):1089-94. doi: 10.1007/s10544-011-9578-7.

DOI:10.1007/s10544-011-9578-7

PMID:21800145

Abstract

This paper describes a simple reusable device that hydrodynamically traps a large number of beads in an array. Guiding pillars allow us to release the trapped beads by simply reversing the flow direction. The trap and reset operations are extremely simple, robust and highly efficient. We analyzed the path of the beads in a microchannel with pillars to optimize the design of the device. We succeeded in arraying hundreds of 100 μm microbeads, subsequently released them in a few minutes, and demonstrated multiple experiments with a single device.

摘要

本文介绍了一种简单的可重复使用的装置，该装置可在微通道中利用流体力将大量珠子捕获在阵列中。导向柱允许我们通过简单地改变流动方向来释放被困的珠子。捕获和重置操作非常简单、稳定且高效。我们分析了带有导向柱的微通道中珠子的路径，以优化装置的设计。我们成功地排列了数百个 100μm 的微珠，随后在几分钟内将它们释放，并使用单个装置演示了多个实验。