Palo Alto, CA 94304, USA.
Curr Hypertens Rep. 2011 Oct;13(5):362-9. doi: 10.1007/s11906-011-0223-x.
Hypertension is extremely common in patients with end-stage renal disease who are receiving hemodialysis, and cardiovascular disease remains the leading cause of death in these patients. However, optimal blood pressure management strategies in this high-risk population are still controversial. This review first discusses the complex association of systolic blood pressure with clinical outcomes in patients on hemodialysis, with a focus on several recent studies. Next, it updates the reader on issues related to optimal timing and methods of blood pressure measurement, appropriate blood pressure targets, and pharmacologic and nonpharmacologic hypertension treatment strategies for patients on hemodialysis.
高血压在接受血液透析的终末期肾病患者中极为常见,心血管疾病仍然是这些患者死亡的主要原因。然而,在这个高危人群中,最佳血压管理策略仍存在争议。这篇综述首先讨论了收缩压与血液透析患者临床结局之间的复杂关系,并重点关注了几项最近的研究。接下来,它更新了读者关于最佳血压测量时机和方法、合适的血压目标以及血液透析患者的药物和非药物降压治疗策略等相关问题。