Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Bioorg Med Chem Lett. 2011 Sep 15;21(18):5393-7. doi: 10.1016/j.bmcl.2011.07.004. Epub 2011 Jul 13.
Five new prenylated acylphloroglucinols, yojironins E-Ι (1-5), were isolated from the whole plants of Hypericum yojiroanum. Their structures were elucidated by spectroscopic data. Yojironin E (1) exhibited antimicrobial activity against Aspergillus niger, Candida albicans, Cryptococcus neoformans, and Trichophyton mentagrophytes.
从圆叶牡荆全株中分离得到五个新的苯丙酰基间苯三酚衍生物,即约伊罗因 E-Ι(1-5)。通过光谱数据分析确定了它们的结构。约伊罗因 E(1)对黑曲霉、白色念珠菌、新型隐球菌和须癣毛癣菌具有抗菌活性。