Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
J Nat Prod. 2012 Mar 23;75(3):484-8. doi: 10.1021/np200741x. Epub 2011 Nov 10.
Two new tetracyclic prenylated acylphloroglucinols, chipericumins A (1) and B (2), were isolated from the roots of Hypericum chinense, together with two new tricyclic prenylated acylphloroglucinols, chipericumins C (3) and D (4). Their structures were elucidated by spectroscopic data. Chipericumins A-D (1-4) are prenylated acylphloroglucinols having a spiro skeleton with an acyl group, a methyl group, a C(5) unit, and a monoterpene moiety in common.
从贯叶连翘的根部分离得到两种新的四环倍半萜酰基间苯三酚类化合物,chipericumins A(1)和 B(2),以及两种新的三环倍半萜酰基间苯三酚类化合物,chipericumins C(3)和 D(4)。通过光谱数据阐明了它们的结构。chipericumins A-D(1-4)是具有螺骨架的酰基间苯三酚类化合物,共同具有酰基、甲基、C(5)单元和单萜部分。