Department of Marine Environmental Engineering, Gyeaongsang National University, Republic of Korea.
Mar Pollut Bull. 2011 Oct;62(10):2264-8. doi: 10.1016/j.marpolbul.2011.07.008. Epub 2011 Jul 30.
To determine the impact of genetic toxicity caused by the Hebei Spirit oil spill on December 7, 2007, we measured DNA damage in the blood cells of striped beakperch in vitro after exposure to extracts from sediments in the Taean area. The objective of this study was to investigate temporal changes of toxic effects caused by residual PAHs in the sediments up to 18 months after an oil spill. In conclusion, DNA damage had reduced over this 18-month period; that is, the sediments recovered quickly from the oil pollution. In addition, statistically significant correlations between PAHs and DNA damage were observed. Because the comet assay is sensitive to DNA damage induced by genotoxic substances from the polluted sediments, the comet assay can be considered a useful tool as a biomarker in investigating genetic toxicity in environmental monitoring and elucidating the recovery of oil pollution after oil spill as well.
为了确定 2007 年 12 月 7 日河北精神石油泄漏造成的遗传毒性的影响，我们测量了暴露于泰安地区沉积物提取物后体外条纹鲈鱼血细胞中的 DNA 损伤。本研究的目的是调查在溢油后 18 个月内沉积物中残留多环芳烃引起的毒性效应的时间变化。总之，DNA 损伤在这 18 个月期间减少了;也就是说，沉积物从石油污染中迅速恢复。此外，还观察到 PAHs 与 DNA 损伤之间存在显著的统计学相关性。由于彗星试验对受污染沉积物中遗传毒性物质诱导的 DNA 损伤敏感，因此彗星试验可以被认为是一种有用的工具，作为环境监测中遗传毒性的生物标志物，并阐明溢油后石油污染的恢复情况。
