Cooke R W
Department of Child Health, University of Liverpool.
Arch Dis Child. 1990 Feb;65(2):201-6. doi: 10.1136/adc.65.2.201.
Eighty one very low birthweight survivors with cerebral palsy were matched with controls by sex, gestational age, and place of birth. Using discriminant analysis, the perinatal profiles for infants with cerebral palsy and their controls were shown to differ significantly. When infants with various types of cerebral palsy were analysed with their controls the discriminating variables differed. Diplegic infants could be differentiated from controls on antenatal variables alone, but significant discrimination of hemiplegic and quadriplegic infants required the addition of postnatal variables. Cranial ultrasound appearances differed appreciably between types of cerebral palsy. Future studies should differentiate between types of cerebral palsy and include ultrasound data. Cerebral palsy in very low birthweight infants is unlikely to prove a useful outcome indicator for neonatal intensive care.
81名极低出生体重的脑瘫幸存者按照性别、胎龄和出生地与对照组进行匹配。通过判别分析发现,脑瘫婴儿及其对照组的围产期特征存在显著差异。当对不同类型脑瘫的婴儿与其对照组进行分析时,判别变量有所不同。仅通过产前变量就能将双侧瘫婴儿与对照组区分开来,但要显著区分偏瘫和四肢瘫婴儿则需要加入产后变量。不同类型脑瘫的头颅超声表现有明显差异。未来的研究应区分不同类型的脑瘫,并纳入超声数据。极低出生体重婴儿的脑瘫不太可能成为新生儿重症监护的有用结局指标。