出生体重、孕周及母亲产科病史对脑瘫出生患病率的影响。
Effects of birth weight, gestational age, and maternal obstetric history on birth prevalence of cerebral palsy.
作者信息
Pharoah P O, Cooke T, Rosenbloom L, Cooke R W
机构信息
Department of Community Health, University of Liverpool.
出版信息
Arch Dis Child. 1987 Oct;62(10):1035-40. doi: 10.1136/adc.62.10.1035.
A register of children with cerebral palsy born to mothers resident in the Mersey region from 1966 to 1977 was compiled from health service records. Frequency distributions and prevalences of birth weight and gestational age differed for those with hemiplegia, diplegia, and quadriplegia. In particular, the children with diplegia showed a bimodal frequency distribution. Children of normal birth weight with diplegia had a higher prevalence of severe mental retardation than those of low birth weight. These differences may be due to survival bias and may not be of aetiological importance. Furthermore, the mothers of diplegic infants had a significantly higher proportion of spontaneous abortions, stillbirths, and low birthweight infants in their obstetric history. This suggests that prenatal factors predominate in the aetiology of diplegia.
一份关于1966年至1977年居住在默西地区的母亲所生脑瘫儿童的登记册是根据医疗服务记录汇编而成的。偏瘫、双瘫和四肢瘫患儿的出生体重和胎龄的频率分布及患病率有所不同。特别是，双瘫患儿呈现出双峰频率分布。正常出生体重的双瘫患儿重度智力发育迟缓的患病率高于低出生体重患儿。这些差异可能是由于生存偏差导致的，可能在病因学上并不重要。此外，双瘫婴儿的母亲在产科病史中自然流产、死产和低体重婴儿的比例明显更高。这表明产前因素在双瘫病因中占主导地位。
Zotero 插件