Sukenik S, Buskila D, Neumann L, Kleiner-Baumgarten A, Zimlichman S, Horowitz J
Rheumatology Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Ann Rheum Dis. 1990 Feb;49(2):99-102. doi: 10.1136/ard.49.2.99.
Forty patients with classical or definite rheumatoid arthritis in a stage of active disease were treated for two weeks at a spa hotel. The patients were divided into four groups of 10. Group I was treated with daily mud packs, group II with daily hot sulphur baths, group III with a combination of mud packs and hot sulphur baths, and group IV served as a control group. The patients were assessed by a rheumatologist who was blinded to the treatment modalities. Statistically significant improvement for a period of up to three months was observed in the three treatment groups in most of the clinical indices. Improvement in the control group was minor in comparison and not statistically significant. No significant improvement was observed in any of the laboratory variables measured. Except for three mild cases of thermal reaction there were no side effects.
40例处于疾病活动期的典型或确诊类风湿关节炎患者在一家温泉酒店接受了为期两周的治疗。患者被分为4组,每组10人。第一组每天接受泥敷治疗,第二组每天接受热硫磺浴治疗,第三组接受泥敷和热硫磺浴联合治疗,第四组作为对照组。由对治疗方式不知情的风湿病专家对患者进行评估。在大多数临床指标方面,三个治疗组在长达三个月的时间内均观察到具有统计学意义的改善。相比之下,对照组的改善较小且无统计学意义。在所测量的任何实验室变量中均未观察到显著改善。除3例轻度热反应外,未出现副作用。