Geach Timothy J, Zimmerman Lyle B
National Institute for Medical Research, London, UK.
Methods Mol Biol. 2011;770:77-117. doi: 10.1007/978-1-61779-210-6_4.
The diploid pipid frog Xenopus tropicalis has recently emerged as a powerful new model system for combining genetic and genomic analysis of tetrapod development with embryological and biochemical assays. Its early development closely resembles that of its well-understood tetraploid relative Xenopus laevis, from which techniques and reagents can be readily transferred, but its compact genome is highly syntenic with those of amniotes. Genetic approaches are facilitated by the large number of embryos produced and the ease of haploid genetics and gynogenesis.
二倍体滑爪蟾热带爪蟾最近成为了一个强大的新模型系统，可将四足动物发育的遗传和基因组分析与胚胎学及生化分析相结合。它的早期发育与人们熟知的四倍体近亲非洲爪蟾非常相似，技术和试剂可以很容易地从非洲爪蟾转移过来，而且它紧凑的基因组与羊膜动物的基因组高度同源。大量产出的胚胎以及单倍体遗传学和雌核发育的简便性促进了遗传学方法的应用。
