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重度原发性产后出血(PPH)后的情绪和身体健康结局:一项多中心队列研究

Emotional and physical health outcomes after significant primary post-partum haemorrhage (PPH): a multicentre cohort study.

作者信息

Thompson Jane F, Roberts Christine L, Ellwood David A

机构信息

Women's Hospitals Australasia, School of Clinical Medicine and Department of Obstetrics and Gynaecology, Australian National University Medical School, Canberra, Australian Capital Territory, Australia.

出版信息

Aust N Z J Obstet Gynaecol. 2011 Aug;51(4):365-71. doi: 10.1111/j.1479-828X.2011.01317.x. Epub 2011 Jun 9.

Abstract

BACKGROUND

Post-partum haemorrhage (PPH) rates are rising; however, data on the health impact on women are lacking.

AIMS

To describe the emotional and physical health outcomes for women following PPH.

METHODS

A cohort of 206 women with primary PPH of 1500 mL or more, and/or peripartum fall in haemoglobin concentration to 7 g/dL or less, and/or of 4 g/dL or less, was recruited from 17 Australian/New Zealand hospitals. Women completed questionnaires in the first week, and at two and four months post-partum. Obstetric details came from hospital records. Outcomes were anxiety; post-natal depression (PND); fatigue; post-traumatic stress disorder (PTSD); general health (SF-36); physical health problems; post-natal bleeding duration; hospital readmission.

RESULTS

Eighty-three percent completed the two-month and 81% the four-month questionnaires; 28% reported bleeding continuously for more than six weeks; 10% required hospital readmission within two months. Anxiety scores were in the medium range; 11 and 13% were at risk of PND at two and four months, respectively; median total fatigue scores were 17 at two and 15 at four months; 5% showed evidence of PTSD at two and 3% at four months; women scored highly in most SF-36 categories and showed improvements over time in all but general and mental health. Physical health concerns were comparable to those reported for general post-natal populations, with the exception of uterine infection (6% at two months).

CONCLUSIONS

In a cohort of women experiencing PPH, emotional and physical health outcomes were similar to those reported in general post-natal populations, with the exception of post-natal bleeding duration, uterine infection and hospital readmission.

摘要

背景

产后出血(PPH)发生率正在上升;然而,缺乏关于其对女性健康影响的数据。

目的

描述产后出血女性的情绪和身体健康状况。

方法

从澳大利亚/新西兰的17家医院招募了206名原发性产后出血1500毫升及以上,和/或围产期血红蛋白浓度降至7克/分升及以下,和/或降至4克/分升及以下的女性。女性在产后第一周、两个月和四个月时完成问卷调查。产科详细信息来自医院记录。结果包括焦虑;产后抑郁症(PND);疲劳;创伤后应激障碍(PTSD);总体健康(SF - 36);身体健康问题;产后出血持续时间;再次入院。

结果

83%的女性完成了两个月的问卷调查,81%完成了四个月的问卷调查;28%报告出血持续超过六周;10%在两个月内需要再次入院。焦虑评分处于中等范围;在两个月和四个月时,分别有11%和13%的女性有患产后抑郁症的风险;两个月时总疲劳评分中位数为17,四个月时为15;在两个月时,5%的女性有创伤后应激障碍的迹象,四个月时为3%;女性在SF - 36的大多数类别中得分较高,除总体健康和心理健康外,其他方面均随时间有所改善。身体健康问题与一般产后人群报告的情况相当,但子宫感染除外(两个月时为6%)。

结论

在经历产后出血的女性队列中,除产后出血持续时间、子宫感染和再次入院外,情绪和身体健康状况与一般产后人群报告的情况相似。

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