HIV阳性患者的黑热病后皮肤利什曼病：两例研究。

Shah Sejal, Shah Aditya, Prajapati Sachin, Bilimoria Freny

Department of Dermatology and Venerology, SBKS Medical College and Research Centre, Pipariya, Waghodia, Gujarat, India.

Indian J Sex Transm Dis AIDS. 2010 Jan;31(1):42-4. doi: 10.4103/0253-7184.69001.

Cutaneous leishmaniasis and human immunodeficiency virus (HIV) co-infection is emerging as increasingly frequent and serious new disease. Leishmaniasis may be acquired before or after HIV infection. We describe two cases of post-kala-azar dermal leishmaniasis in HIV-positive patients. Both the patients had papulonodular lesions on upper extremities and back with low CD4 count. Slit skin smear with giemsa stain revealed Leishman Donovan (LD) bodies and skin biopsy of both the patients revealed lymphohistiocytic infiltrate with numerous intracytoplasmic LD bodies.

皮肤利什曼病与人类免疫缺陷病毒（HIV）合并感染正日益成为一种愈发常见且严重的新疾病。利什曼病可能在HIV感染之前或之后感染。我们描述了两例HIV阳性患者患黑热病后皮肤利什曼病的病例。两名患者上肢和背部均有丘疹结节性病变，CD4细胞计数较低。吉姆萨染色的皮肤涂片显示杜氏利什曼原虫（LD）小体，两名患者的皮肤活检均显示淋巴细胞组织细胞浸润，并伴有大量胞浆内LD小体。