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肝滤泡树突状细胞肉瘤:一种罕见肿瘤的不常见表现及文献复习。

Follicular dendritic cell sarcoma of the liver: unusual presentation of a rare tumor and literature review.

机构信息

Department of Surgery, Division of Hepatobiliary Surgery and Transplantation, New York Medical College, Westchester Medical Center, 95 Grassland Road, Valhalla, NY 10595, USA.

出版信息

Hepatobiliary Pancreat Dis Int. 2011 Aug;10(4):443-5. doi: 10.1016/s1499-3872(11)60076-3.

DOI:10.1016/s1499-3872(11)60076-3
PMID:21813397
Abstract

BACKGROUND

Hepatic follicular dendritic cell (FDC) sarcoma is an extremely rare neoplasm. Most commonly, FDC sarcoma presents as a solitary mass in lymph nodes, however, several extra-nodal locations have been identified.

METHODS

We report a case of a 53-year-old female who presented with symptoms of abdominal pain, fever, anemia, and jaundice. After an extensive review of the literature, we have found only 12 cases of hepatic FDC sarcoma.

RESULTS

The tumor was 11.5 cm in diameter and composed of spindle and epithelioid cells with ovoid nuclei and associated with mixed inflammatory infiltrate. Immunohistochemical stains were positive for CD35 and CD21. The patient underwent a left hepatic lobectomy.

CONCLUSIONS

Liver follicular dendritic cell sarcoma is a very rare tumor. Most cases present with abdominal pain and weight loss, and most of them can be managed by hepatic resection with excellent short-term outcomes.

摘要

背景

肝滤泡树突状细胞(FDC)肉瘤是一种极为罕见的肿瘤。FDC 肉瘤最常见的表现为淋巴结孤立性肿块,但也有多个结外部位的报道。

方法

我们报告了一例 53 岁女性患者,其表现为腹痛、发热、贫血和黄疸。在广泛查阅文献后,我们仅发现 12 例肝 FDC 肉瘤。

结果

肿瘤直径为 11.5 厘米,由梭形和上皮样细胞组成,具有卵圆形核,并伴有混合性炎症浸润。免疫组织化学染色 CD35 和 CD21 阳性。患者接受了左半肝切除术。

结论

肝滤泡树突状细胞肉瘤是一种非常罕见的肿瘤。大多数病例表现为腹痛和体重减轻,大多数病例可以通过肝切除术进行治疗,短期疗效极佳。

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