Panigrahi Chinmayee, Nayak Hemanta K, Patra Susama, Mitra Suvradeep
Department of Pathology and Laboratory Medicine, AIIMS, Bhubaneswar, 751019, India.
Department of Gastroenterology, AIIMS, Bhubaneswar, 751019, India.
J Clin Exp Hepatol. 2022 Mar-Apr;12(2):677-685. doi: 10.1016/j.jceh.2021.06.014. Epub 2021 Jun 19.
Follicular dendritic cell (FDC) sarcoma is an uncommon tumor of the liver with only 30 previous cases reported in the English literature. Histopathological examination is the gold standard for the diagnosis of FDC sarcoma although the diagnosis is often missed because of its rarity. It usually presents with spindle-cell morphology although epithelioid/biphasic morphology is also well-known. This morphological variation can also pose a diagnostic challenge. We discuss a case of unresectable hepatic FDC sarcoma in an adult male who was diagnosed in core biopsy. We highlight the relevant histomorphological differentials and diagnostic approaches to FDC sarcoma in this anecdote.
滤泡树突状细胞（FDC）肉瘤是一种罕见的肝脏肿瘤，英文文献中此前仅报道过30例。组织病理学检查是诊断FDC肉瘤的金标准，不过由于其罕见性，诊断往往会被漏诊。它通常表现为梭形细胞形态，尽管上皮样/双相形态也较为常见。这种形态学变异也可能带来诊断挑战。我们讨论一例成年男性不可切除的肝脏FDC肉瘤病例，该病例通过粗针活检得以诊断。在这一病例中，我们强调了FDC肉瘤相关的组织形态学鉴别诊断及诊断方法。
