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酵母中的转座元件。

Transposable elements in yeasts.

机构信息

CNRS UMR 7156, Laboratoire Génétique Moléculaire Génomique Microbiologie, Université de Strasbourg, 28 rue Goethe, 67083 Strasbourg cedex, France.

出版信息

C R Biol. 2011 Aug-Sep;334(8-9):679-86. doi: 10.1016/j.crvi.2011.05.017. Epub 2011 Jul 5.

Abstract

With the development of new sequencing technologies in the past decade, yeast genomes have been extensively sequenced and their structures investigated. Transposable elements (TEs) are ubiquitous in eukaryotes and constitute a limited part of yeast genomes. However, due to their ability to move in genomes and generate dispersed repeated sequences, they contribute to modeling yeast genomes and thereby induce plasticity. This review assesses the TE contents of yeast genomes investigated so far. Their diversity and abundance at the inter- and intraspecific levels are presented, and their effects on gene expression and genome stability is considered. Recent results concerning TE-host interactions are also analyzed.

摘要

在过去十年中,随着新测序技术的发展,酵母基因组得到了广泛的测序和结构研究。转座元件(TEs)在真核生物中普遍存在,构成了酵母基因组的有限部分。然而,由于它们在基因组中移动和产生分散重复序列的能力,它们有助于模拟酵母基因组,从而诱导可塑性。本综述评估了迄今为止研究过的酵母基因组中的 TE 含量。展示了它们在种间和种内水平的多样性和丰度,并考虑了它们对基因表达和基因组稳定性的影响。还分析了最近关于 TE-宿主相互作用的结果。

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