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全动脉弓去分支术治疗广泛主动脉弓疾病是否安全?27 例单中心经验。

Is total debranching a safe procedure for extensive aortic-arch disease? A single experience of 27 cases.

机构信息

Vascular and Endovascular Surgery Unit, Mauriziano Umberto I Hospital, Largo Turati 62, 10128 Turin, Italy.

出版信息

Eur J Cardiothorac Surg. 2012 Jan;41(1):177-82. doi: 10.1016/j.ejcts.2011.05.058.

Abstract

OBJECTIVE

Thoracic, arch, and proximal descending thoracic aorta diseases are still considered an enormous challenge. The hybrid approach developed in recent years (supra-aortic trunks debranching and thoracic endovascular repair aortic repair; TEVAR) may improve the morbidity and mortality of the population at risk. The aim of this study was to analyze retrospectively our experience in the hybrid treatment of aortic-arch aneurysms and dissections.

METHOD

We carried out a retrospective review of 27 patients who required a surgical debranching of the supra-aortic trunks and a TEVAR in the management of the aortic arch and proximal descending thoracic aortic disease. The aortic lesions included 18 degenerative arch-aortic aneurysms, four complicated aortic dissections, two subclavian artery aneurysms, and three penetrating atherosclerotic ulcers. Technical success was achieved in all patients.

RESULTS

The 30-day mortality rate was 11.1% (3/27). Mean follow-up was 16.7 months (range, 1-56), and the survival rate was 77.8%. The endoleaks' rate was 3.7% (1/27), due to a stent-graft migration.

CONCLUSION

Hybrid approaches may represent an alternative option in the treatment of complex aortic lesions involving the arch and the proximal descending thoracic aorta in high-risk patients and emergency cases. However, the promising early results need to be confirmed by longer follow-up and larger comparative series.

摘要

目的

胸主动脉、主动脉弓和降主动脉近端疾病仍然是一个巨大的挑战。近年来发展起来的杂交治疗方法(主动脉弓部分支去分支术和胸主动脉腔内修复术;TEVAR)可能会降低高危人群的发病率和死亡率。本研究旨在回顾性分析我们在主动脉弓部病变杂交治疗方面的经验。

方法

我们回顾性分析了 27 例需要行主动脉弓部分支去分支术和 TEVAR 的患者,这些患者患有主动脉弓和降主动脉近端疾病。主动脉病变包括 18 例退行性主动脉弓部动脉瘤、4 例复杂主动脉夹层、2 例锁骨下动脉动脉瘤和 3 例穿透性粥样硬化性溃疡。所有患者均达到技术成功。

结果

30 天死亡率为 11.1%(3/27)。平均随访时间为 16.7 个月(范围 1-56 个月),生存率为 77.8%。1 例(3.7%)发生内漏,是由于支架移植物迁移所致。

结论

在高危患者和紧急情况下,杂交治疗方法可能是治疗涉及主动脉弓和降主动脉近端的复杂主动脉病变的一种替代选择。然而,更长时间的随访和更大的对照系列研究需要证实这一有前途的早期结果。

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