Rodríguez-Artalejo Fernando, Graciani Auxiliadora, Guallar-Castillón Pilar, León-Muñoz Luz M, Zuluaga M Clemencia, López-García Esther, Gutiérrez-Fisac Juan Luis, Taboada José M, Aguilera M Teresa, Regidor Enrique, Villar-Álvarez Fernando, Banegas José R
Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad Autónoma de Madrid/IdiPaz, Madrid, España.
Rev Esp Cardiol. 2011 Oct;64(10):876-82. doi: 10.1016/j.recesp.2011.05.019. Epub 2011 Aug 6.
The ENRICA study aims to assess the frequency and distribution of the main components of the natural history of cardiovascular disease in Spain, including food consumption and other behavioral risk factors, biological risk factors, early damage of target organs, and diagnosed morbidity.
A cross-sectional survey of 11,991 individuals representative of the non-institutionalized population aged 18 years and older in Spain was conducted from June 2008 to October 2010. Data collection comprised 3 sequential stages: a) computer-assisted telephone interview to obtain information on lifestyle, knowledge and attitudes about cardiovascular disease risk factors, and the signs and symptoms of heart attack and stroke, subjective health, and morbidity; b) first home visit, to collect blood and urine samples for analysis by a central laboratory, and c) second home visit, to measure anthropometric variables and blood pressure and to administer a computer-assisted dietary history; data on functional limitations are also collected from participants aged 65 years and older.
The ENRICA study has shown the feasibility of a large home-based health interview and examination survey in Spain. It will provide valuable information to support and evaluate national strategies against cardiovascular disease and other chronic diseases in Spain. Moreover, a 3-year prospective follow-up of the study participants, including a new physical exam, is planned to start in the second semester of 2011 and will update lifestyle information and biological variables. (ClinicalTrials.gov number, NCT01133093).
ENRICA研究旨在评估西班牙心血管疾病自然史主要组成部分的发生频率和分布情况，包括食物消费及其他行为风险因素、生物风险因素、靶器官早期损害以及已确诊的发病率。
2008年6月至2010年10月，对西班牙11991名18岁及以上非机构化人口的代表性个体进行了横断面调查。数据收集包括3个连续阶段：a）计算机辅助电话访谈，以获取有关生活方式、对心血管疾病风险因素的知识和态度、心脏病发作和中风的体征和症状、主观健康状况以及发病率的信息；b）首次家访，采集血液和尿液样本以供中央实验室分析；c）第二次家访，测量人体测量变量和血压，并进行计算机辅助饮食史调查；还从65岁及以上的参与者那里收集功能受限数据。
ENRICA研究表明在西班牙进行大规模基于家庭的健康访谈和检查调查是可行的。它将提供有价值的信息，以支持和评估西班牙针对心血管疾病和其他慢性病的国家战略。此外，计划于2011年下半年开始对研究参与者进行为期3年的前瞻性随访，包括一次新的体格检查，这将更新生活方式信息和生物变量。（ClinicalTrials.gov编号，NCT01133093）
