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一种用于儿童肾活检的简单自动化设备:可获得更多组织的优势。

A simple automated device for children's renal biopsy: advantage in obtaining more tissue.

机构信息

Department of Nephrology, Dong Fang Hospital, Medical College of Xiamen University, Fuzhou, Fujian, China.

出版信息

J Clin Pathol. 2011 Nov;64(11):1029-31. doi: 10.1136/jclinpath-2011-200004. Epub 2011 Aug 6.

DOI:10.1136/jclinpath-2011-200004
PMID:21821863
Abstract

Sufficient tissue yield is essential for renal biopsy. We have developed a simple automated renal biopsy device (Chen device) that constantly obtains more tissue. Since the Bard device is extensively used around the world, we compared our device with the Bard device. Pediatric patients were biopsied with either the Chen (n=247) or Bard (n=200) devices. No major complications were encountered and the incidence of minor complications was comparable between two devices. However, the average length of tissue obtained by the Chen device per biopsy (1.78±0.73 cm) was significantly longer than that obtained by the Bard device (1.23±0.45 cm). Accordingly, 61.94% of biopsies with the Chen device had 20 or more glomeruli, whereas only 18% of biopsies with the Bard device had this number (p<0.001). Thus, the Chen device has the advantage of obtaining more renal tissue per biopsy while being equally efficient and safe as the Bard device.

摘要

足够的组织量对于肾活检至关重要。我们开发了一种简单的自动肾活检设备(Chen 设备),它可以持续获得更多的组织。由于 Bard 设备在全球范围内广泛使用,我们将我们的设备与 Bard 设备进行了比较。使用 Chen 设备(n=247)或 Bard 设备(n=200)对儿科患者进行了活检。两种设备均未发生重大并发症,且轻微并发症的发生率相似。然而,Chen 设备每例活检获得的组织平均长度(1.78±0.73 cm)明显长于 Bard 设备(1.23±0.45 cm)。因此,Chen 设备 61.94%的活检有 20 个或更多肾小球,而 Bard 设备只有 18%的活检有这么多肾小球(p<0.001)。因此,Chen 设备在每例活检中获得更多肾组织的同时,与 Bard 设备一样高效和安全。

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J Clin Pathol. 2011 Nov;64(11):1029-31. doi: 10.1136/jclinpath-2011-200004. Epub 2011 Aug 6.
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