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微创 Nuss 手术治疗 406 例漏斗胸患儿的经验。

Experience in minimally invasive Nuss operation for 406 children with pectus excavatum.

机构信息

Department of Cardiothoracic Surgery, Children's Hospital, Zhejiang University School of Medicine, and Zhejiang Key Laboratory for Diagnosis and Treatment of Neonatal Diseases, Hangzhou, 310003, China.

出版信息

World J Pediatr. 2011 Aug;7(3):257-61. doi: 10.1007/s12519-011-0319-z. Epub 2011 Aug 7.

DOI:10.1007/s12519-011-0319-z
PMID:21822992
Abstract

BACKGROUND

This study was to investigate the advantages of thoracoscopy-assisted minimally invasive Nuss operation for the treatment of pectus excavatum (PE) in children.

METHODS

A total of 406 patients with PE (female: 93; male: 313) with an average age of 6.8 years (range: 3.5-17.5 years) were included in this study. Associated diseases included congenital heart disease in 9 patients and congenital pulmonary cyst in 2. The Haller index of the patients ranged from 3.35 to 7.23, with an average of 5.17±1.64. Minimally invasive Nuss operation was performed for all the patients.

RESULTS

The operations were performed successfully and no operative mortality occurred. The average blood loss during the operation was less than 10 mL and the operating time ranged from 30 to 85 minutes with an average of 45 minutes. The length of hospital stay ranged from 5 to 9 days with an average of 7 days. Struts were implanted in 12 (3.0%) of the 406 patients. Injury of the pericardium occurred in 1 patient during the operation. Early post-operative complications occurred in 9 patients with pneumothorax and 6 patients with pleural effusion, which were cured by puncture or drainage. Poor wound healing occurred in 4 patients (1.0%) and was cured by nutritional support. During a 3-month to 6-year follow-up, 2 patients had scoliosis and 3 patients had displacement of the strut, which was cured by a second Nuss operation. Allergy occurred in 2 patients: the symptoms were improved in 1 patient after conservative treatment, but the strut was removed in advance due to allergy in the other patient. Totally 154 patients (40.0%) underwent operation for strut removal. Excellent repair results were achieved in 387 (95.3%) patients, good repair results in 12 (3.0%), and fair results in 7 (1.7%).

CONCLUSIONS

Thoracoscopy-assisted Nuss operation has many advantages including small and masked incision, short operative time, minimal blood loss, fast recovery, less trauma, and satisfactory outcomes of repair. Nuss is a safe and reliable technique for repair of PE.

摘要

背景

本研究旨在探讨胸腔镜辅助微创 Nuss 手术治疗儿童漏斗胸(PE)的优势。

方法

本研究共纳入 406 例 PE 患者(女性 93 例,男性 313 例),平均年龄 6.8 岁(3.5-17.5 岁)。合并疾病包括 9 例先天性心脏病和 2 例先天性肺囊肿。患者的 Haller 指数为 3.35-7.23,平均为 5.17±1.64。所有患者均行微创 Nuss 手术。

结果

手术均顺利完成,无手术死亡。术中平均出血量少于 10ml,手术时间 30-85 分钟,平均 45 分钟。住院时间 5-9 天,平均 7 天。406 例患者中 12 例(3.0%)植入支架。1 例患者术中出现心包损伤。9 例患者术后早期出现气胸,6 例患者出现胸腔积液,经穿刺或引流治愈。4 例(1.0%)患者伤口愈合不良,经营养支持治愈。3 个月至 6 年随访中,2 例患者出现脊柱侧弯,3 例患者支架移位,再次行 Nuss 手术治愈。2 例患者发生过敏:1 例经保守治疗后症状改善,另 1 例因过敏提前取出支架。共 154 例(40.0%)患者行支架取出术。387 例(95.3%)患者修复效果优良,12 例(3.0%)良好,7 例(1.7%)一般。

结论

胸腔镜辅助 Nuss 手术具有切口小、隐蔽、手术时间短、出血量少、恢复快、创伤小、修复效果满意等优点。Nuss 技术是治疗 PE 的一种安全可靠的方法。

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本文引用的文献

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Extending the use of Nuss procedure in patients older than 30 years.将 Nuss 手术的应用扩展至 30 岁以上患者。
Eur J Cardiothorac Surg. 2011 Aug;40(2):334-7. doi: 10.1016/j.ejcts.2010.11.040. Epub 2011 Jan 12.
2
Twenty-one years of experience with minimally invasive repair of pectus excavatum by the Nuss procedure in 1215 patients.21 年微创 Nuss 手术治疗漏斗胸 1215 例经验。
Ann Surg. 2010 Dec;252(6):1072-81. doi: 10.1097/SLA.0b013e3181effdce.
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Indications and technique of Nuss procedure for pectus excavatum.
Pectus cross bars increase hospital readmission rates due to serous pleural effusion.
鸡胸横条会因浆液性胸腔积液而增加医院再入院率。
Gen Thorac Cardiovasc Surg. 2022 Apr;70(4):352-358. doi: 10.1007/s11748-021-01732-z. Epub 2021 Nov 16.
4
An Initial 5-Year Single-Center Experience of 365 Patients Undergoing the Video-Assisted Thoracoscopic Surgery for Nuss Procedure for Pectus Excavatum in Resource-Scare Setting.在资源匮乏环境下365例漏斗胸患者接受胸腔镜辅助Nuss手术的单中心5年初步经验
Front Surg. 2021 Jun 14;8:693562. doi: 10.3389/fsurg.2021.693562. eCollection 2021.
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Metal allergy after the Nuss procedure for pectus excavatum: a review.漏斗胸Nuss手术后的金属过敏:综述
Postepy Dermatol Alergol. 2020 Dec;37(6):848-852. doi: 10.5114/ada.2020.102094. Epub 2021 Jan 6.
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Pectus excavatum and congenital cystic lung lesion: simultaneous surgery advocated.漏斗胸与先天性肺囊性病变:提倡同期手术。
J Thorac Dis. 2018 Nov;10(11):6230-6237. doi: 10.21037/jtd.2018.10.8.
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Acquired scoliosis following Nuss procedure for pectus excavatum: A case report.漏斗胸Nuss手术后获得性脊柱侧弯:一例报告。
Medicine (Baltimore). 2019 Jan;98(1):e13855. doi: 10.1097/MD.0000000000013855.
8
Video-assisted-thoracoscopic surgery in left-to-right Nuss procedure for pectus excavatum for prevention of serious complications - technical aspects based on 1006 patients.胸腔镜辅助下 Nuss 手术治疗漏斗胸由左至右操作以预防严重并发症——基于 1006 例患者的技术要点
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Complex corrective procedure in surgical treatment of asymmetrical pectus excavatum.漏斗胸不对称畸形手术治疗中的复杂矫正手术
Kardiochir Torakochirurgia Pol. 2017 Jun;14(2):110-114. doi: 10.5114/kitp.2017.68741. Epub 2017 Jun 30.
漏斗胸 Nuss 手术的适应证和技术。
Thorac Surg Clin. 2010 Nov;20(4):583-97. doi: 10.1016/j.thorsurg.2010.07.002.
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Nuss operation for pectus excavatum: a single-institution experience.Nuss 手术治疗漏斗胸:单中心经验。
World J Pediatr. 2009 Nov;5(4):292-5. doi: 10.1007/s12519-009-0055-9. Epub 2009 Nov 13.
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Peri-operative data on the Nuss procedure in children with pectus excavatum: independent survey of the first 20 years' data.漏斗胸儿童Nuss手术的围手术期数据:对前20年数据的独立调查
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Pectus excavatum: historical background, clinical picture, preoperative evaluation and criteria for operation.漏斗胸:历史背景、临床表现、术前评估及手术标准
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Complications associated with the Nuss procedure: continued evolution of the learning curve.与努斯手术相关的并发症:学习曲线的持续演变。
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