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圈套辅助式结肠镜检查在结肠镜下黏膜切除术(EMR)中的应用:一项随机对照试验。

Usefulness of cap-assisted colonoscopy during colonoscopic EMR: a randomized, controlled trial.

机构信息

Department of Internal Medicine, Chonnam National University Medical School, Gwangju, South Korea.

出版信息

Gastrointest Endosc. 2011 Oct;74(4):869-75. doi: 10.1016/j.gie.2011.06.005. Epub 2011 Aug 6.

Abstract

BACKGROUND

Clinical demand for total colonoscopy is increasing. Several articles have reported on the usefulness of a cap for faster cecal intubation and reduced patient discomfort, but results for polyp and adenoma detection have been inconsistent.

OBJECTIVE

To assess the efficacy of a cap attached to the tip of a colonoscope for detection and resection of polyps by experienced colonoscopists.

DESIGN

Prospective, randomized, controlled trial.

SETTING

A tertiary referral center.

PATIENTS AND INTERVENTION

A total of 329 patients who underwent colonoscopic EMR were randomized to cap-assisted colonoscopy (CAC) (CAC group, n = 166) or regular colonoscopy (RC) (RC group, n = 163).

MAIN OUTCOME MEASUREMENTS

Cecal intubation time, total procedure time, required time for colonoscopic EMR of each polyp, and missing polyp rate.

RESULTS

The cecal intubation time in the CAC group and RC group was 5.3 ± 3.3 minutes and 5.8 ± 3.7 minutes, respectively (P = .170). The total procedure time in the CAC group and RC group was 23.0 ± 15.5 minutes and 29.2 ± 13.4 minutes, respectively (P = .626). The time required for colonoscopic EMR of each polyp in the CAC group and RC group was 3.5 ± 4.5 minutes and 4.2 ± 5.1 minutes, respectively (P = .010). The number of polyps during the initial colonoscopy in the CAC group and RC group was 2.2 ± 1.7 and 2.0 ± 1.8, respectively (P = .221). The number of detected polyps during colonoscopic EMR in the CAC group and RC group was 3.4 ± 2.7 and 2.7 ± 1.9 (P = .003). The number of missed polyps in the CAC group and RC group was 1.1 ± 1.5 and 0.8 ± 0.9 (P = .024).

LIMITATION

Single-center experience.

CONCLUSIONS

CAC may reduce the time required for colonoscopic EMR of each polyp and may also improve the polyp detection rate.

摘要

背景

临床对全结肠镜检查的需求正在增加。有几篇文章报道了使用套帽可以更快地插管并减少患者不适,但息肉和腺瘤的检出率结果不一致。

目的

评估在有经验的结肠镜检查医师中,在结肠镜前端加帽是否能提高息肉的检出和切除效果。

设计

前瞻性、随机、对照试验。

地点

三级转诊中心。

患者和干预措施

共 329 例接受结肠镜下黏膜切除术的患者被随机分为套帽辅助结肠镜检查(CAC)组(CAC 组,n = 166)或常规结肠镜检查(RC)组(RC 组,n = 163)。

主要观察指标

盲肠插管时间、总操作时间、每个息肉行结肠镜下黏膜切除术所需的时间和漏检息肉率。

结果

CAC 组和 RC 组的盲肠插管时间分别为 5.3 ± 3.3 分钟和 5.8 ± 3.7 分钟(P =.170)。CAC 组和 RC 组的总操作时间分别为 23.0 ± 15.5 分钟和 29.2 ± 13.4 分钟(P =.626)。CAC 组和 RC 组每个息肉行结肠镜下黏膜切除术所需的时间分别为 3.5 ± 4.5 分钟和 4.2 ± 5.1 分钟(P =.010)。CAC 组和 RC 组初始结肠镜检查时的息肉数量分别为 2.2 ± 1.7 个和 2.0 ± 1.8 个(P =.221)。CAC 组和 RC 组结肠镜下黏膜切除术时检出的息肉数量分别为 3.4 ± 2.7 个和 2.7 ± 1.9 个(P =.003)。CAC 组和 RC 组漏检的息肉数量分别为 1.1 ± 1.5 个和 0.8 ± 0.9 个(P =.024)。

局限性

单中心经验。

结论

CAC 可能缩短每个息肉行结肠镜下黏膜切除术所需的时间,并可能提高息肉检出率。

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