Department of Thoracic Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University, College of Medicine, Taipei, Taiwan, Republic of China.
Am J Med Sci. 2012 Apr;343(4):267-72. doi: 10.1097/MAJ.0b013e31822a6bc3.
Despite removal of airway metallic stents by rigid bronchoscope was presented, there are few reports describing such removal by flexible bronchoscope.
36 patients who had airway Ultraflex stents removed by flexible bronchoscope from 2002 to 2009 were reviewed. Factors contributing to removal method and complications during and after removal were analyzed by multinomial logistic regression.
Among 36 patients with stent extraction; 17 stents (47.2%) were removed by a single procedure and 19 (52.8%) by multiple procedures. There was no mortality or severe morbidity during or after stent removal. There were 21 complications after stent removal, including retained stent pieces (n = 9), mucosal tear with bleeding (n = 5), and re-obstruction requiring silicone stent placement (n = 7). Stent indwelling time >10 months (adjusted odds ratio: 9.5; 95% confidence interval: 7.9-11.1, P=0.01), obstructive granulation tissue formation before stent removal (adjusted odds ratio: 5.2; 95% confidence interval: 2.2-8.6, P=0.01), and stent fracture before removal (adjusted odds ratio: 3.5; 95% confidence interval: 1.8-15.4, P=0.04) were independent predictors of the need for multiple procedures for stent removal. Stent indwelling time >10 months (adjusted odds ratio: 4.2; 95% confidence interval: 2.1-8.9, P=0.01), obstructive granulation tissue formation before stent removal (adjusted odds ratio: 16.5; 95% confidence interval, 1.8-49.6, P=0.01), and multiple procedures required for removal (adjusted odds ratio: 6.9; 95% confidence interval, 1.1-43.5, P=0.04) were independent predictors of removal complications.
A flexible bronchoscope can be used to remove stents in patients with central airway obstruction and stent-related complications. This procedure should be performed in centers with experienced multidisciplinary teams.
尽管已经有通过硬式支气管镜移除气道金属支架的报道,但通过软式支气管镜来移除气道 Ultraflex 支架的报道却很少。
回顾了 2002 年至 2009 年间通过软式支气管镜成功移除 36 例气道 Ultraflex 支架的患者。通过多项逻辑回归分析,研究了影响移除方法和移除过程中及移除后并发症的相关因素。
36 例支架取出患者中,17 例(47.2%)通过单次手术取出,19 例(52.8%)通过多次手术取出。在支架取出过程中和取出后,均无死亡或严重并发症发生。支架取出后有 21 例发生并发症,包括支架残片残留(9 例)、黏膜撕裂伴出血(5 例)和再次阻塞需要放置硅胶支架(7 例)。支架留置时间>10 个月(调整后的优势比:9.5;95%置信区间:7.9-11.1,P=0.01)、支架取出前存在阻塞性肉芽组织形成(调整后的优势比:5.2;95%置信区间:2.2-8.6,P=0.01)和支架取出前发生断裂(调整后的优势比:3.5;95%置信区间:1.8-15.4,P=0.04)是需要多次手术取出支架的独立预测因素。支架留置时间>10 个月(调整后的优势比:4.2;95%置信区间:2.1-8.9,P=0.01)、支架取出前存在阻塞性肉芽组织形成(调整后的优势比:16.5;95%置信区间,1.8-49.6,P=0.01)和需要多次手术取出(调整后的优势比:6.9;95%置信区间,1.1-43.5,P=0.04)是支架取出并发症的独立预测因素。
软式支气管镜可用于治疗中央气道阻塞和与支架相关的并发症患者。该操作应在有经验的多学科团队的中心进行。