Department of Dermatology, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Arch Dermatol Res. 2011 Nov;303(9):623-4. doi: 10.1007/s00403-011-1165-5.
Vitiligo is an acquired clinical conundrum, characterized by white areas on the skin due to loss of functional melanocytes. Various studies demonstrated that vitiligo is associated with fewer risk of skin cancer but no exact molecular explanation for this interesting observation has been described. This article reviews the exist documents and provides a molecular mechanism for this negative association.
白癜风是一种获得性临床难题，其特征是由于功能性黑素细胞丧失导致皮肤出现白色区域。各种研究表明，白癜风患者皮肤癌的风险较低，但对于这一有趣观察结果的确切分子机制尚未描述。本文回顾了现有文献，并为这种负相关提供了分子机制。
