Masciello A L
University of Florida Health Science Center, Jacksonville.
Obstet Gynecol. 1990 May;75(5):834-8.
Several studies document the benefit of dorsal penile nerve block for neonatal circumcision, but the literature does not address the use of local anesthesia. A randomized, controlled, prospective study was conducted to compare the efficacy of dorsal penile nerve block versus local anesthesia. Thirty infants were randomly divided into three equal groups (N = 10): an unanesthetized control group, a group given dorsal penile nerve block, and a group given local anesthesia. Heart rate, transcutaneous oxygen saturation, and crying were monitored continuously before, during, and after circumcision. During circumcision, both the dorsal penile nerve block group and the local-anesthesia group demonstrated smaller increases in heart rate, smaller drops in oxygen saturation, and less crying compared with unanesthetized controls (P less than .05). Both techniques worked well in anesthetizing the dorsal aspect of the penis; however, during those steps of circumcision involving trauma to the ventral aspect of the penis, the local-anesthesia group demonstrated smaller increases in heart rate and less crying compared with infants given dorsal penile nerve block (P less than .05). Cortisol levels measured 30 minutes postoperatively were lower in the local-anesthesia group than in either the controls or the dorsal penile nerve block group (P less than .05). Dorsal penile nerve block had no effect on postoperative cortisol levels. No complications occurred. Although both types of anesthesia attenuated the physiologic responses to circumcision, local anesthesia demonstrated greater efficacy than dorsal penile nerve block while being simpler to perform.
多项研究证实了阴茎背神经阻滞用于新生儿包皮环切术的益处,但文献中未涉及局部麻醉的应用。我们进行了一项随机、对照、前瞻性研究,以比较阴茎背神经阻滞与局部麻醉的效果。30名婴儿被随机分为三组,每组10名:未麻醉对照组、接受阴茎背神经阻滞组和接受局部麻醉组。在包皮环切术前、术中及术后持续监测心率、经皮血氧饱和度和哭声。在包皮环切术中,与未麻醉对照组相比,阴茎背神经阻滞组和局部麻醉组的心率升高幅度较小、血氧饱和度下降幅度较小且哭声较少(P<0.05)。两种技术在麻醉阴茎背侧方面均效果良好;然而,在包皮环切术涉及阴茎腹侧创伤的步骤中,与接受阴茎背神经阻滞的婴儿相比,局部麻醉组的心率升高幅度较小且哭声较少(P<0.05)。术后30分钟测量的皮质醇水平在局部麻醉组低于对照组或阴茎背神经阻滞组(P<0.05)。阴茎背神经阻滞对术后皮质醇水平无影响。未发生并发症。虽然两种麻醉方式均减轻了包皮环切术的生理反应,但局部麻醉显示出比阴茎背神经阻滞更大的效果,且操作更简单。