Akkermans J P, Kuiper C J, Rondhuis P R, Wirahadiredja R M
Tijdschr Diergeneeskd. 1979 Mar 15;104(6):255-62.
When Aujeszky's disease was detected on a large pig-breeding farm, all normal sows and boars were vaccinated with an ethyl-ethylene-imine (EEI) vaccine produced in the Bundesforschungsanstalt für Viruskrankheiten der Tiere (Federal Research Institute for Viruses Diseases in Animals) in Tübbingen, Western Germany. The vaccine contained DEAE dextran as an adjuvant. The vaccine was inoculated twice by intramuscular route at a three weeks' interval, 5 ml. being inoculated at one time. Hyperimmune serum was inoculated in young pigs. In addition, hygienic procedures were adopted, consisting in disinfection and isolation. The disease was successfully controlled within eight weeks. Sows which developed Aujeszky's disease showed hardly any symptoms suggesting lesions of the central nervous system. Pulmonary lesions were the outstanding clinical feature. The semen quality of the affected male swine had markedly deteriorated. This was resorted to normal, however, within from five to ten weeks. The incidence of abortion and piglet mortality were low. In view of the results of virological and serological studies, it was concluded that the persistence of this strain of virus (causing Aujeszky's disease) was very slight.
在一个大型养猪场检测到奥耶斯基氏病后，所有健康的母猪和公猪都接种了由位于西德图宾根的联邦动物病毒病研究所生产的乙基乙烯亚胺（EEI）疫苗。该疫苗含有作为佐剂的二乙氨基乙基葡聚糖。疫苗通过肌肉注射途径分两次接种，间隔三周，每次接种5毫升。对仔猪接种了高免血清。此外，还采取了包括消毒和隔离在内的卫生措施。该病在八周内得到成功控制。感染奥耶斯基氏病的母猪几乎没有表现出任何提示中枢神经系统病变的症状。肺部病变是突出的临床特征。患病公猪的精液质量明显恶化。不过，在五到十周内恢复正常。流产率和仔猪死亡率较低。根据病毒学和血清学研究结果，得出结论，该病毒株（导致奥耶斯基氏病）的持续性非常轻微。
