Department of Chemistry, Laboratory of Natural Products, Faculty of Sciences, University of Monastir, Monastir 5000, Tunisia.
Nat Prod Res. 2012;26(3):235-42. doi: 10.1080/14786419.2010.536950. Epub 2011 Aug 11.
Two new phytochemical compounds, Tetranins A and B, 1-(3,5'-dihydroxy-4'-méthoxyphenyl)-2-phenylethanol 1 and 5,2'-dihydroxy-5'-methoxy-6,7-methylenedioxy-isoflavone 2, were isolated from the EtOAc extract of Salsola tetrandra roots. They exhibited a significant antioxidant effect in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and 2,2'-azinobis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Their structures were elucidated by extensive spectroscopic methods including 1-D-((1)H and (13)C) and 2-D-NMR experiments (CHcorr, HMBC, (1)H-(1)H COSY and NOESY) as well as high-resolution ES-MS and they were found to be quite active as antioxidants in the DPPH and ABTS assays.
从四翅滨藜根的 EtOAc 提取物中分离得到了两种新的植物化学化合物，即 Tetranins A 和 B，1-(3,5'-二羟基-4'-甲氧基苯基)-2-苯乙醇 1 和 5,2'-二羟基-5'-甲氧基-6,7-亚甲基二氧基异黄酮 2。它们在 1,1-二苯基-2-苦基肼（DPPH）自由基和 2,2'-联氮双（3-乙基苯并噻唑啉-6-磺酸）（ABTS）测定中表现出显著的抗氧化作用。通过广泛的光谱方法（包括 1-D-（（1）H 和（13）C）和 2-D-NMR 实验（CHcorr、HMBC、（1）H-（1）H COSY 和 NOESY）以及高分辨率 ES-MS）阐明了它们的结构，并发现它们在 DPPH 和 ABTS 测定中作为抗氧化剂具有相当高的活性。
