Payan M J, Xerri L, Moncada K, Bastid C, Agostini S, Sastre B, Sahel J, Choux R
Laboratoire d'Anatomie Pathologique, Hôpital Sainte-Marguerite, Marseille, France.
Am J Gastroenterol. 1990 Apr;85(4):459-63.
This report deals with two cases of villous adenoma of the Wirsung duct. The two patients presented with upper abdominal pain, diarrhea, and weight loss. Duodenal intubation showed a complete failure of exocrine pancreatic function. Ultrasound scan, computed tomography, and endoscopic retrograde cholangiopancreatography disclosed marked dilatation of the head portion of the main pancreatic duct. A proximal duodenopancreatectomy was performed. Pathological examination revealed a papillary polyp expanding the pancreatic head and filling the main duct lumen. Histological pattern consisted of a villous adenoma without any feature of malignant change. Previously reported cases exhibit many similarities to our two cases. The putative likelihood of malignant change and the relationship between villous tumors of the Wirsung duct and of other origin remain unclear.
本报告涉及两例胰腺导管绒毛状腺瘤病例。两名患者均表现为上腹部疼痛、腹泻和体重减轻。十二指肠插管显示外分泌胰腺功能完全丧失。超声扫描、计算机断层扫描和内镜逆行胰胆管造影显示主胰管头部明显扩张。进行了近端十二指肠胰腺切除术。病理检查发现一个乳头状息肉，使胰头扩大并充满主导管腔。组织学模式为绒毛状腺瘤，无任何恶变特征。先前报道的病例与我们的两例病例有许多相似之处。胰腺导管绒毛状肿瘤恶变的假定可能性以及与其他起源的绒毛状肿瘤之间的关系仍不清楚。
