Polyclonal immunoglobulin free light chains as a potential biomarker of immune stimulation and inflammation.
作者信息
Hutchison Colin A, Landgren Ola
机构信息
Renal Institute of Birmingham, Department of Nephrology, University of Birmingham and University Hospital Birmingham, Birmingham, UK.
出版信息
Clin Chem. 2011 Oct;57(10):1387-9. doi: 10.1373/clinchem.2011.169433.
Abstract
摘要
相似文献
1
Polyclonal immunoglobulin free light chains as a potential biomarker of immune stimulation and inflammation.多克隆免疫球蛋白游离轻链作为免疫刺激和炎症的潜在生物标志物。
Clin Chem. 2011 Oct;57(10):1387-9. doi: 10.1373/clinchem.2011.169433.
2
The relationship between high-sensitivity CRP and polyclonal free light chains as markers of inflammation in chronic disease.高敏C反应蛋白与多克隆游离轻链作为慢性病炎症标志物之间的关系。
Int J Lab Hematol. 2014 Aug;36(4):415-24. doi: 10.1111/ijlh.12159. Epub 2013 Nov 5.
3
The Impact of Immunomodulatory Treatment on Kappa Free Light Chains as Biomarker in Neuroinflammation.免疫调节治疗对神经炎症中κ 轻链作为生物标志物的影响。
Cells. 2020 Mar 31;9(4):842. doi: 10.3390/cells9040842.
4
Elevated Concentrations of Serum Immunoglobulin Free Light Chains in Systemic Lupus Erythematosus Patients in Relation to Disease Activity, Inflammatory Status, B Cell Activity and Epstein-Barr Virus Antibodies.系统性红斑狼疮患者血清游离免疫球蛋白轻链浓度升高与疾病活动、炎症状态、B细胞活性及EB病毒抗体的关系
PLoS One. 2015 Sep 24;10(9):e0138753. doi: 10.1371/journal.pone.0138753. eCollection 2015.
5
Immunoglobulin free light chains: an inflammatory biomarker of diabetes.游离免疫球蛋白轻链：糖尿病的一种炎症生物标志物。
Inflamm Res. 2020 Aug;69(8):715-718. doi: 10.1007/s00011-020-01357-7. Epub 2020 May 18.
6
Is early, deep free light chain response really an adverse prognostic factor?早期、深度游离轻链反应真的是一个不良预后因素吗？
Blood. 2008 Feb 15;111(4):2490-1; author reply 2491. doi: 10.1182/blood-2007-11-125849.
7
Paraproteinemia and serum protein electrophoresis interpretation.副蛋白血症与血清蛋白电泳解读
Ann Allergy Asthma Immunol. 2019 Jan;122(1):11-16. doi: 10.1016/j.anai.2018.08.004.
8
Proteomics profiling of swine serum following lipopolysaccharide stimulation.猪血清脂多糖刺激后的蛋白质组学分析。
Rapid Commun Mass Spectrom. 2020 Apr 15;34(7):e8639. doi: 10.1002/rcm.8639.
9
Determination of free light chains: assay-dependent differences in interpretation.游离轻链的测定：不同检测方法在解读上的差异。
Clin Chem Lab Med. 2020 Sep 2;59(2):e69-e71. doi: 10.1515/cclm-2020-0938.
10
Reference ranges of the Sebia free light chain ratio in patients with chronic kidney disease.慢性肾病患者中赛比亚游离轻链比值的参考范围。
Clin Chem Lab Med. 2018 Aug 28;56(9):e232-e234. doi: 10.1515/cclm-2018-0040.
引用本文的文献
1
Comparison of middle molecule removal with expanded hemodialysis versus haemodiafiltration among Chinese hemodialysis patients.中国血液透析患者中，高通量血液透析与血液透析滤过清除中分子物质的比较。
Ren Fail. 2025 Dec;47(1):2498093. doi: 10.1080/0886022X.2025.2498093. Epub 2025 May 29.
2
Effects of aerobic and resistance exercise for 9 months on serum free light chains in type 2 diabetes.9个月的有氧运动和抗阻运动对2型糖尿病患者血清游离轻链的影响。
Front Physiol. 2024 Apr 25;15:1328470. doi: 10.3389/fphys.2024.1328470. eCollection 2024.
3
Elevated serum polyclonal immunoglobulin free light chains in patients with severe asthma.重度哮喘患者血清多克隆游离免疫球蛋白轻链升高。
Front Pharmacol. 2023 Jun 16;14:1126535. doi: 10.3389/fphar.2023.1126535. eCollection 2023.
4
Myeloma precursor disease (MGUS) among rescue and recovery workers exposed to the World Trade Center disaster.暴露于世界贸易中心灾难中的救援和恢复工作人员中的骨髓瘤前期疾病（MGUS）。
Blood Cancer J. 2022 Aug 22;12(8):120. doi: 10.1038/s41408-022-00709-2.
5
Alpha-1 antitrypsin deficiency research and emerging treatment strategies: what's down the road?α-1抗胰蛋白酶缺乏症的研究与新兴治疗策略：未来走向如何？
Ther Adv Chronic Dis. 2021 Jul 29;12_suppl:20406223211014025. doi: 10.1177/20406223211014025. eCollection 2021.
6
Serum immunoglobulin free light chain levels in systemic autoimmune rheumatic diseases.系统性自身免疫性风湿病患者血清免疫球蛋白游离轻链水平。
Clin Exp Immunol. 2020 Feb;199(2):163-171. doi: 10.1111/cei.13385. Epub 2019 Oct 31.
7
Association of elevated serumfree light chains with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.血清游离轻链升高与慢性淋巴细胞白血病和单克隆 B 细胞淋巴增生症的关系。
Blood Cancer J. 2019 Aug 5;9(8):59. doi: 10.1038/s41408-019-0220-x.
8
B cell homeostasis is maintained during long-duration spaceflight.B 细胞在长时间的太空飞行中保持着内稳态。
J Appl Physiol (1985). 2019 Feb 1;126(2):469-476. doi: 10.1152/japplphysiol.00789.2018. Epub 2018 Nov 29.
9
Abnormal Plasma Cell Disorders in Refinery Waste Workers.炼油厂废物处理工人的异常浆细胞疾病
J Clin Med. 2018 Aug 17;7(8):221. doi: 10.3390/jcm7080221.
10
Multiple Myeloma and Its Precursor Disease Among Firefighters Exposed to the World Trade Center Disaster.消防员暴露于世界贸易中心灾难后患多发性骨髓瘤及其前体细胞疾病。
JAMA Oncol. 2018 Jun 1;4(6):821-827. doi: 10.1001/jamaoncol.2018.0509.
本文引用的文献
1
Circulating serum free light chains as predictive markers of AIDS-related lymphoma.循环血清游离轻链作为 AIDS 相关淋巴瘤的预测标志物。
J Clin Oncol. 2010 Feb 10;28(5):773-9. doi: 10.1200/JCO.2009.25.1322. Epub 2010 Jan 4.
2
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis.C-反应蛋白浓度与冠心病、卒中和死亡风险的关系：一项个体参与者荟萃分析。
Lancet. 2010 Jan 9;375(9709):132-40. doi: 10.1016/S0140-6736(09)61717-7. Epub 2009 Dec 22.
3
Evidence of serum immunoglobulin abnormalities up to 9.8 years before diagnosis of chronic lymphocytic leukemia: a prospective study.在慢性淋巴细胞白血病诊断前长达 9.8 年的血清免疫球蛋白异常证据：一项前瞻性研究。
Blood. 2009 Dec 3;114(24):4928-32. doi: 10.1182/blood-2009-08-237651. Epub 2009 Oct 14.
4
International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders.国际骨髓瘤工作组关于多发性骨髓瘤及相关疾病血清游离轻链分析的指南。
Leukemia. 2009 Feb;23(2):215-24. doi: 10.1038/leu.2008.307. Epub 2008 Nov 20.
5
Quantitative assessment of serum and urinary polyclonal free light chains in patients with chronic kidney disease.慢性肾病患者血清和尿液多克隆游离轻链的定量评估
Clin J Am Soc Nephrol. 2008 Nov;3(6):1684-90. doi: 10.2215/CJN.02290508.
6
The evolving use of serum free light chain assays in haematology.血清游离轻链检测在血液学中的应用进展
Br J Haematol. 2008 May;141(4):413-22. doi: 10.1111/j.1365-2141.2008.07079.x. Epub 2008 Mar 3.
7
C-reactive protein and the risk of incident colorectal cancer.C反应蛋白与结直肠癌发病风险
JAMA. 2004 Feb 4;291(5):585-90. doi: 10.1001/jama.291.5.585.
8
9
Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine.用于血清和尿液中游离免疫球蛋白轻链的高灵敏度自动化免疫测定法。
Clin Chem. 2001 Apr;47(4):673-80.
10
The renal handling of low molecular weight proteins. II. Disorders of serum protein catabolism in patients with tubular proteinuria, the nephrotic syndrome, or uremia.低分子量蛋白质的肾脏处理。II. 肾小管蛋白尿、肾病综合征或尿毒症患者血清蛋白分解代谢紊乱
J Clin Invest. 1972 Aug;51(8):2162-74. doi: 10.1172/JCI107023.
Zotero 插件