Agarwal Amit, Allan Joshua J
R & D Centre, Natural Remedies, Bangalore, India.
J Ayurveda Integr Med. 2010 Apr;1(2):129-31. doi: 10.4103/0975-9476.65092.
Evaluation of herbs for antifertility effects has been in progress worldwide for several decades to identify effective and safe substances for control of population explosion. Inspite of availability of internationally accepted guidelines for the assessment of reproductive toxicity/antifertility potential of test substances, many published articles, on critical review, seem to lack reproducibility and are thus likely to mislead both the scientific community and the general public. This paper, while emphasizing the importance of generating authentic toxicity/safety information on acclaimed medicinal herbs, spells out existing pitfalls in such studies, and explores some control measures worth considering in times to come.
几十年来,全球一直在评估草药的抗生育作用,以确定有效且安全的物质来控制人口爆炸。尽管有国际公认的测试物质生殖毒性/抗生育潜力评估指南,但许多已发表的文章经严格审查后似乎缺乏可重复性,因此可能会误导科学界和公众。本文在强调生成关于著名草药的真实毒性/安全性信息的重要性的同时,阐明了此类研究中存在的陷阱,并探讨了一些未来值得考虑的控制措施。