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[肾细胞癌]

[Renal cell carcinoma].

作者信息

Fornara P, Hoda M R

机构信息

Universitätsklinik und Poliklinik für Urologie und Nierentransplantation, Martin-Luther-Universität Halle-Wittenberg, Ernst Grube-Strasse 40, Halle, Germany.

出版信息

Urologe A. 2011 Sep;50 Suppl 1:219-22. doi: 10.1007/s00120-011-2677-5.

DOI:10.1007/s00120-011-2677-5
PMID:21837488
Abstract

Approximately 85% of all malignant tumors of the kidney are renal cell carcinomas (RCC). Sonography is the leading examination for early detection of kidney tumors. The treatment of RCC has been enriched in recent years by new therapeutic options for localized and metastatic cancer. The classification of RCC is based on TNM and UICC criteria. The so-called Motzer criteria are being increasingly employed to assess prognosis and monitor therapy and as the basis for reaching decisions on choosing the type of systemic treatment.

摘要

所有肾恶性肿瘤中约85%为肾细胞癌(RCC)。超声检查是早期发现肾肿瘤的主要检查方法。近年来,针对局限性和转移性癌症的新治疗选择丰富了肾细胞癌的治疗手段。肾细胞癌的分类基于TNM和UICC标准。所谓的Motzer标准越来越多地用于评估预后、监测治疗,并作为决定选择全身治疗类型的依据。

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本文引用的文献

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ICUD-EAU International Consultation on Kidney Cancer 2010: treatment of metastatic disease.2010 年国际肾脏肿瘤研讨会(ICUD-EAU):转移性疾病的治疗。
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青蒿琥酯通过细胞周期阻滞和诱导铁死亡抑制舒尼替尼耐药肾癌细胞的生长。
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Renal cell neoplasias: reversion-inducing cysteine-rich protein with Kazal motifs discriminates tumor subtypes, while extracellular matrix metalloproteinase inducer indicates prognosis.肾细胞肿瘤:含Kazal基序的富含半胱氨酸的逆转诱导蛋白可区分肿瘤亚型,而细胞外基质金属蛋白酶诱导剂则可提示预后。
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Surgical management of localised renal cell carcinoma.局限性肾细胞癌的外科治疗
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N Engl J Med. 2010 Feb 18;362(7):624-34. doi: 10.1056/NEJMcp0910041.
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Current state of urological cryosurgery: prostate and kidney.泌尿外科冷冻手术的现状:前列腺和肾脏
BJU Int. 2010 Mar;105(5):590-600. doi: 10.1111/j.1464-410X.2010.09235.x.
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Optimal management of metastatic renal cell carcinoma: an algorithm for treatment.转移性肾细胞癌的优化管理:一种治疗算法
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Radical nephrectomy with and without lymph-node dissection: final results of European Organization for Research and Treatment of Cancer (EORTC) randomized phase 3 trial 30881.根治性肾切除术伴或不伴淋巴结清扫术:欧洲癌症研究与治疗组织(EORTC)随机 3 期试验 30881 的最终结果。
Eur Urol. 2009 Jan;55(1):28-34. doi: 10.1016/j.eururo.2008.09.052. Epub 2008 Oct 1.
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Targeted therapy for advanced renal cell carcinoma.晚期肾细胞癌的靶向治疗
Cochrane Database Syst Rev. 2008 Apr 16;2008(2):CD006017. doi: 10.1002/14651858.CD006017.pub2.
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Positive margins in laparoscopic partial nephrectomy in 855 cases: a multi-institutional survey from the United States and Europe.855例腹腔镜部分肾切除术切缘阳性情况:一项来自美国和欧洲的多机构调查
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