Department of Cardiac Surgery, Children's Hospital Boston and Harvard Medical School, Boston, Mass, USA.
J Thorac Cardiovasc Surg. 2011 Nov;142(5):1098-107, 1107.e1-5. doi: 10.1016/j.jtcvs.2011.07.003. Epub 2011 Aug 15.
Our objective was to define the relationship between surgical technical performance score, intraoperative adverse events, and major postoperative adverse events in complex pediatric cardiac repairs.
Infants younger than 6 months were prospectively followed up until discharge from the hospital. Technical performance scores were graded as optimal, adequate, or inadequate based on discharge echocardiograms and need for reintervention after initial surgery. Case complexity was determined by Risk Adjustment in Congenital Heart Surgery (RACHS-1) category, and preoperative illness severity was assessed by Pediatric Risk of Mortality (PRISM) III score. Intraoperative adverse events were prospectively monitored. Outcomes were analyzed using nonparametric methods and a logistic regression model.
A total of 166 patients (RACHS 4-6 [49%]), neonates [50%]) were observed. Sixty-one (37%) had at least 1 intraoperative adverse event, and 47 (28.3%) had at least 1 major postoperative adverse event. There was no correlation between intraoperative adverse events and RACHS, preoperative PRISM III, technical performance score, or postoperative adverse events on multivariate analysis. For the entire cohort, better technical performance score resulted in lower postoperative adverse events, lower postoperative PRISM, and lower length of stay and ventilation time (P < .001). Patients requiring intraoperative revisions fared as well as patients without, provided the technical score was at least adequate.
In neonatal and infant open heart repairs, technical performance score is one of the main predictors of postoperative morbidity. Outcomes are not affected by intraoperative adverse events, including surgical revisions, provided technical performance score is at least adequate.
本研究旨在明确复杂儿科心脏修复术中手术技术表现评分、术中不良事件与主要术后不良事件之间的关系。
对 6 个月以下的婴儿进行前瞻性随访,直至出院。根据出院时的超声心动图和初次手术后是否需要再次干预,将技术表现评分分为优、良和差。手术难度通过先天性心脏病风险调整(RACHS-1)分类确定,术前疾病严重程度通过儿科死亡风险(PRISM)III 评分评估。术中不良事件进行前瞻性监测。采用非参数方法和逻辑回归模型分析结果。
共观察了 166 例患者(RACHS 4-6[49%],新生儿[50%])。61 例(37%)至少发生 1 次术中不良事件,47 例(28.3%)至少发生 1 次主要术后不良事件。多变量分析显示,术中不良事件与 RACHS、术前 PRISM III、技术表现评分或术后不良事件之间无相关性。对于整个队列,技术表现评分越高,术后不良事件、术后 PRISM、住院时间和通气时间越低(P<.001)。只要技术评分至少为良,术中需要修订的患者与无需修订的患者预后一样。
在新生儿和婴儿的心脏直视修复术中,技术表现评分是术后发病率的主要预测因素之一。只要技术表现评分至少为良,就不会因术中不良事件(包括手术修订)而影响结局。