Ben Mahmoud Lobna, Ghozzi Hanène, Hakim Ahmed, Sahnoun Zouheir, Zeghal Khaled
Regional Centre of Pharmacovigilance of Sfax, Department of Pharmacology, Sfax University for the South, Tunisia.
J Infect Dev Ctries. 2011 Aug 12;5(8):596-8. doi: 10.3855/jidc.1363.
Chronic urticaria is one of the most frequent skin diseases in medical practice. Urticaria is defined as acute if the whealing persists for less than six weeks and as chronic if it persists for longer. Chronic urticaria that lasts for several years to decades significantly impairs the quality of life. There is evidence that Helicobacter pylori has a critical role in different extragastric diseases such as chronic urticaria. We present a case of chronic urticaria in an adult patient with H. pylori infection and disease regression after triple anti-H. pylori therapy. In contrast to the autoimmune mechanisms involved in chronic urticaria against which no specific treatment strategy has been developed, infections with H. pylori could be treated with triple therapy. It is suggested that laboratory tests for the detection of this pathogen should be performed in patients with chronic urticaria.
慢性荨麻疹是医疗实践中最常见的皮肤病之一。如果风团持续时间少于六周，则荨麻疹被定义为急性；如果持续时间更长，则为慢性。持续数年至数十年的慢性荨麻疹会严重损害生活质量。有证据表明，幽门螺杆菌在诸如慢性荨麻疹等不同的胃外疾病中起关键作用。我们报告一例成年幽门螺杆菌感染患者的慢性荨麻疹病例，该患者在接受三联抗幽门螺杆菌治疗后疾病消退。与慢性荨麻疹所涉及的自身免疫机制不同，针对自身免疫机制尚未制定出具体的治疗策略，而幽门螺杆菌感染可用三联疗法治疗。建议对慢性荨麻疹患者进行检测该病原体的实验室检查。
