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两种不同形式的清漆治疗牙本质过敏症的比较:一项受试者盲法随机临床研究。

Comparison of two different forms of varnishes in the treatment of dentine hypersensitivity: a subject-blind randomised clinical study.

作者信息

Sethna Gulnar Dara, Prabhuji M L V, Karthikeyan B V

机构信息

Department of Periodontics, Krishnadevaraya College of Dental Sciences, Bangalore, Karnataka, India.

出版信息

Oral Health Prev Dent. 2011;9(2):143-50.

Abstract

PURPOSE

Dentine hypersensitivity is one of the most frequently recorded complaints of dental discomfort. Current evidence implicates patent dentinal tubules in hypersensitive dentine, and it follows that one effective way to reduce dentine sensitivity is to occlude the dentinal tubules. The purpose of this study was to compare the efficacy of two different desensitising agents, Cervitec varnish and Gluma varnish.

MATERIALS AND METHODS

Two hundred fifty patients self-reporting dentine hypersensitivity completed the paired split mouth randomised, subject-blind study. Each participant had a minimum of two sensitive teeth in at least two different quadrants and displaying a response of ≥3 cm to an evaporative stimulus. The hypersensitivity levels were measured with a tactile stimulus (scratchometer), thermal stimulus (cold water test), and an evaporative stimulus (air blast test) using a visual analogue scale. The teeth were evaluated immediately after treatment, and at 4 and 12 weeks after application of the chlorhexidine-containing varnish Cervitec and the glutaraldehyde-containing varnish, Gluma Desensitizer.

RESULTS

Statistical analysis indicated that both the desensitising varnishes were effective in alleviating dentine hypersensitivity at all time intervals compared to baseline. There was a highly statistically significantly greater reduction in dentine hypersensitivity to evaporative stimulus, cold stimulus, and tactile stimulus after application of Cervitec than after Gluma Desensitizer (P < 0.001).

CONCLUSION

Both the varnishes have a therapeutic potential to alleviate dentine hypersensitivity at all time intervals compared to baseline. However, Cervitec varnish is more efficacious in reducing dentine hypersensitivity than Gluma varnish at both 4 weeks and 12 weeks post-treatment.

摘要

目的

牙本质敏感是最常记录到的牙齿不适主诉之一。目前的证据表明,敏感牙本质中的牙本质小管是开放的,因此,减少牙本质敏感的一种有效方法是封闭牙本质小管。本研究的目的是比较两种不同脱敏剂——Cervitec 清漆和 Gluma 清漆的疗效。

材料与方法

250 名自述有牙本质敏感的患者完成了配对的半口随机、受试者盲法研究。每位参与者至少在两个不同象限有两颗敏感牙齿,并且对蒸发刺激的反应≥3 cm。使用视觉模拟量表,通过触觉刺激(划痕仪)、热刺激(冷水试验)和蒸发刺激(气枪试验)测量过敏水平。在使用含氯己定的 Cervitec 清漆和含戊二醛的 Gluma 脱敏剂治疗后立即、4 周和 12 周对牙齿进行评估。

结果

统计分析表明,与基线相比,两种脱敏清漆在所有时间间隔均能有效减轻牙本质敏感。应用 Cervitec 后,对蒸发刺激、冷刺激和触觉刺激的牙本质敏感降低程度在统计学上显著高于应用 Gluma 脱敏剂后(P < 0.001)。

结论

与基线相比,两种清漆在所有时间间隔均有减轻牙本质敏感的治疗潜力。然而,在治疗后 4 周和 12 周,Cervitec 清漆在降低牙本质敏感方面比 Gluma 清漆更有效。

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