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一项基于实践的随机对照试验,旨在研究三种干预措施减轻牙本质过敏症的疗效。

A practice-based randomised controlled trial of the efficacy of three interventions to reduce dentinal hypersensitivity.

作者信息

Gibson M, Sharif M O, Smith A, Saini P, Brunton P A

机构信息

Poulton Dental Practice, Poulton Road, Wallasey, Wirral CH44 9DQ, United Kingdom.

出版信息

J Dent. 2013 Aug;41(8):668-74. doi: 10.1016/j.jdent.2013.06.003. Epub 2013 Jun 18.

Abstract

OBJECTIVES

The aim of this study was to evaluate the efficacy of three different interventions (non-desensitising toothpaste, desensitising toothpaste and professionally applied dentine bonding agent) in reducing dentinal hypersensitivity over a 2-week, 3-month and 6-month-period in a dental practice setting.

METHODS

This was a randomised controlled, single-blind; parallel-group trial conducted in general dental practice by a single general dental practitioner. Seventy-five subjects were randomly allocated to three groups; non-desensitising toothpaste (NDT), desensitising toothpaste (DT) and professionally applied desensitising agent (DA). Dentinal hypersensitivity was measured using a Visual Analogue Scale (VAS) to record the response from a standardised short blast of air from a triple syringe. Dentinal hypersensitivity was recorded at baseline, two weeks, three months and six months for all groups.

RESULTS

Dentinal hypersensitivity reduced significantly (p<0.0001) in both groups DT and DA, in addition the reduction in sensitivity was sustained and continued to improve over a 6-month-period. The greatest reduction in dentinal hypersensitivity was recorded in group DA.

CONCLUSIONS

The results from this study suggest that application of dentine bonding agents, to teeth diagnosed with dentine hypersensitivity provides the greatest improvement in dentine hypersensitivity at 2 weeks and 6 months. This reduction in dentine hypersensitivity is greater than that achieved by the desensitising toothpaste tested and a non-desensitising toothpaste.

摘要

目的

本研究旨在评估三种不同干预措施(非脱敏牙膏、脱敏牙膏和专业应用的牙本质粘结剂)在牙科诊所环境中,于2周、3个月和6个月期间降低牙本质过敏的疗效。

方法

这是一项由一名普通牙科医生在普通牙科诊所进行的随机对照、单盲平行组试验。75名受试者被随机分为三组:非脱敏牙膏组(NDT)、脱敏牙膏组(DT)和专业应用的脱敏剂组(DA)。使用视觉模拟量表(VAS)测量牙本质过敏,以记录来自三联注射器的标准化短时间空气喷射的反应。所有组在基线、两周、三个月和六个月时记录牙本质过敏情况。

结果

DT组和DA组的牙本质过敏均显著降低(p<0.0001),此外,敏感性的降低持续存在,并在6个月期间持续改善。DA组记录到牙本质过敏降低幅度最大。

结论

本研究结果表明,对诊断为牙本质过敏的牙齿应用牙本质粘结剂,在2周和6个月时能最大程度改善牙本质过敏。这种牙本质过敏的降低幅度大于所测试的脱敏牙膏和非脱敏牙膏。

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