Wally Owen, Punja Zamir K
Department of Biological Sciences, Simon Fraser University, Burnaby, BC, Canada.
GM Crops. 2010 Jul-Sep;1(4):199-206. doi: 10.4161/gmcr.1.4.13225.
We review the current and future potential of genetic engineering strategies used to make fungal and bacterial pathogen-resistant GM crops, illustrating different examples of the technologies and the potential benefits and short-falls of the strategies. There are well- established procedures for the production of transgenic plants with resistance towards these pathogens and considerable progress has been made using a range of new methodologies. There are no current commercially available transgenic plant species with increased resistance towards fungal and bacterial pathogens; only plants with increased resistance towards viruses are available. With an improved understanding of plant signaling pathways in response to a range of other pathogens, such as fungi, additional candidate genes for achieving resistance are being investigated. The potential for engineering plants for resistance against individual devastating diseases or for plants with resistance towards multiple pathogens is discussed in detail.
我们回顾了用于培育抗真菌和细菌病原体转基因作物的基因工程策略的现状及未来潜力，举例说明了这些技术的不同实例以及该策略的潜在益处和不足之处。目前已有成熟的程序用于培育对这些病原体具有抗性的转基因植物，并且使用一系列新方法已取得了相当大的进展。目前尚无对真菌和细菌病原体具有增强抗性的转基因植物商业品种；仅有对病毒具有增强抗性的植物。随着对植物响应一系列其他病原体（如真菌）的信号通路的理解不断加深，正在研究更多用于实现抗性的候选基因。本文详细讨论了培育针对个别毁灭性病害具有抗性的植物或对多种病原体具有抗性的植物的潜力。
