Adamson J W, Eschbach J W
New York Blood Center, New York 10021.
Annu Rev Med. 1990;41:349-60. doi: 10.1146/annurev.me.41.020190.002025.
The anemia of chronic renal failure can now be effectively treated with recombinant human erythropoietin when given in adequate doses. This hormone replacement therapy is associated with significant clinical benefits but it requires adequate iron stores for maximal effectiveness, it may result in elevation in diastolic blood pressure, and the response may be blunted by the presence of infection or inflammation.
慢性肾衰竭所致贫血现在通过给予足够剂量的重组人促红细胞生成素能够得到有效治疗。这种激素替代疗法具有显著的临床益处，但为达到最大疗效需要充足的铁储备，它可能导致舒张压升高，而且感染或炎症的存在可能会减弱治疗反应。
