Barma Punyakrit Deb, Ranabir Salam, Prasad Lallan, Singh Thangjam Premchand
Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, India.
Indian J Endocrinol Metab. 2011 Jul;15(Suppl 1):S40-3. doi: 10.4103/2230-8210.83061.
Type 2 diabetes mellitus is the most prevalent form of diabetes worldwide. In western countries majority of the cases are obese. The scenario may be different in certain parts of India. Various studies have reported a high prevalence of lean type 2 diabetes mellitus with a body mass index < 19 kg/m(2).
We evaluated 100 cases of lean type 2 diabetes mellitus (62 males and 38 females).
The mean duration of diabetes was 51.7 months (range 5-180 months). The glycemic control was poor according to standard guidelines. The majority of them showed response to oral hypoglycemic agents. Secondary failure to oral hypoglycemic agents was seen in 27 patients. The prevalence of microvascular complications was much higher than macrovascular complications. Neuropathy was the commonest complication seen in 70%, followed by retinopathy in 25%. Only 12 patients had hypertension, one had coronary artery disease and two had cerebrovascular accident. Lipid profile was not significantly deranged in our patients.
2型糖尿病是全球最常见的糖尿病类型。在西方国家，大多数病例为肥胖型。印度某些地区的情况可能有所不同。各种研究报告称，体重指数<19kg/m²的瘦型2型糖尿病患病率很高。
我们评估了100例瘦型2型糖尿病患者（62例男性和38例女性）。
糖尿病平均病程为51.7个月（范围5 - 180个月）。根据标准指南，血糖控制较差。他们中的大多数对口服降糖药有反应。27例患者出现口服降糖药继发失效。微血管并发症的患病率远高于大血管并发症。神经病变是最常见的并发症，占70%，其次是视网膜病变，占25%。只有12例患者患有高血压，1例患有冠状动脉疾病，2例发生脑血管意外。我们的患者血脂谱无明显紊乱。
