Kochhar Rakesh, Dutta Usha, Miglani Amit, Bhagat Suraj, Poornachandra Kuchhangi Sureshchandra, Vaiphei Kim, Nain Chander K, Singh Kartar
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Gastroenterol. 2011 Jul;30(4):166-9. doi: 10.1007/s12664-011-0106-8. Epub 2011 Aug 17.
Endoscopic findings of celiac disease have high specificity and sensitivity. We evaluated records of 137 consecutive patients who had endotherapy for variceal hemorrhage, and who had features of celiac disease at endoscopy; patients who had such markers at endoscopy had undergone duodenal histology and serology. Thirty-one patients had changes of portal hypertensive vasculopathy in the duodenum, 8 had scalloping, and 6 had mosaic pattern; 3 patients also had decreased fold height or sparse folds in the descending duodenum. Six of these 8 patients had positive serology and histology suggestive of celiac disease. Endoscopic evaluation resulted in diagnosis of CD in 4.37% patients of chronic liver disease undergoing endotherapy.
乳糜泻的内镜检查结果具有高特异性和敏感性。我们评估了137例因静脉曲张出血接受内镜治疗且在内镜检查时有乳糜泻特征的连续患者的记录;在内镜检查时有此类标志物的患者接受了十二指肠组织学检查和血清学检查。31例患者十二指肠有门静脉高压性血管病变改变,8例有扇贝样改变,6例有马赛克样改变;3例患者十二指肠降部皱襞高度降低或皱襞稀疏。这8例患者中有6例血清学和组织学检查呈阳性,提示乳糜泻。内镜评估使4.37%接受内镜治疗的慢性肝病患者被诊断为乳糜泻。